Interaction of 11C-Tariquidar and 11C-Elacridar with P-Glycoprotein and Breast Cancer Resistance Protein at the Human Blood–Brain Barrier

Martin Bauer; Rudolf Karch; Markus Zeitlinger; Johann Stanek; Cécile Philippe; Wolfgang Wadsak; Markus Mitterhauser; Walter Jäger; Helmuth Haslacher; Markus Müller; Oliver Langer

doi:10.2967/jnumed.112.118232

Research ArticleClinical Investigations

Interaction of ¹¹C-Tariquidar and ¹¹C-Elacridar with P-Glycoprotein and Breast Cancer Resistance Protein at the Human Blood–Brain Barrier

Martin Bauer, Rudolf Karch, Markus Zeitlinger, Johann Stanek, Cécile Philippe, Wolfgang Wadsak, Markus Mitterhauser, Walter Jäger, Helmuth Haslacher, Markus Müller and Oliver Langer

Journal of Nuclear Medicine August 2013, 54 (8) 1181-1187; DOI: https://doi.org/10.2967/jnumed.112.118232

Martin Bauer

1Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria

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Rudolf Karch

2Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna, Vienna, Austria

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Markus Zeitlinger

1Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria

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Johann Stanek

1Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria

3Health and Environment Department, AIT Austrian Institute of Technology GmbH, Seibersdorf, Austria

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Cécile Philippe

1Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria

4Department of Nuclear Medicine, Medical University of Vienna, Vienna, Austria

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Wolfgang Wadsak

4Department of Nuclear Medicine, Medical University of Vienna, Vienna, Austria

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Markus Mitterhauser

4Department of Nuclear Medicine, Medical University of Vienna, Vienna, Austria

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Walter Jäger

5Department of Clinical Pharmacy and Diagnostics, University of Vienna, Vienna, Austria; and

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Helmuth Haslacher

6Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria

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Markus Müller

1Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria

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Oliver Langer

1Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria

3Health and Environment Department, AIT Austrian Institute of Technology GmbH, Seibersdorf, Austria

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Journal of Nuclear Medicine

Vol. 54, Issue 8

August 1, 2013

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Interaction of ¹¹C-Tariquidar and ¹¹C-Elacridar with P-Glycoprotein and Breast Cancer Resistance Protein at the Human Blood–Brain Barrier

Martin Bauer, Rudolf Karch, Markus Zeitlinger, Johann Stanek, Cécile Philippe, Wolfgang Wadsak, Markus Mitterhauser, Walter Jäger, Helmuth Haslacher, Markus Müller, Oliver Langer

Journal of Nuclear Medicine Aug 2013, 54 (8) 1181-1187; DOI: 10.2967/jnumed.112.118232

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Interaction of ¹¹C-Tariquidar and ¹¹C-Elacridar with P-Glycoprotein and Breast Cancer Resistance Protein at the Human Blood–Brain Barrier

Martin Bauer, Rudolf Karch, Markus Zeitlinger, Johann Stanek, Cécile Philippe, Wolfgang Wadsak, Markus Mitterhauser, Walter Jäger, Helmuth Haslacher, Markus Müller, Oliver Langer

Journal of Nuclear Medicine Aug 2013, 54 (8) 1181-1187; DOI: 10.2967/jnumed.112.118232

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Keywords

P-glycoprotein
breast cancer resistance protein
blood-brain barrier
11C-tariquidar
11C-elacridar

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Interaction of ¹¹C-Tariquidar and ¹¹C-Elacridar with P-Glycoprotein and Breast Cancer Resistance Protein at the Human Blood–Brain Barrier

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