Article Figures & Data
Figures
- FIGURE 1.
Rotarod treadmill performance. Line shows temporal profile of functional recovery in vehicle- and BMSC-transplanted rats subjected to permanent MCA occlusion (MCAO). *P < 0.05.
- FIGURE 2.
Representative findings of 18F-FDG PET at 6 and 35 d after ischemia. Color (A) and black-and-white (C) images of vehicle-transplanted animals. Color (B) and black-and-white (D) images of BMSC-transplanted rats. There was significant increase in local glucose metabolism in periinfarct neocortex (arrows).
- FIGURE 3.
Bar graphs show ipsilateral-to-contralateral ratio of cerebral glucose utilization in dorsal neocortex adjacent to cerebral infarct (A) and striatum (B). **P < 0.01 (day 6 vs. day 35). ¶¶P < 0.01 (vehicle vs. BMSC).
- FIGURE 4.
Photomicrographs of double immunohistochemistry in periinfarct neocortex (A and C) and ipsilateral hippocampus (B). Most GFP-positive cells (green) were also positive for NeuN (red; arrows in A and B) and GFAP (red; arrow in C). Scale bars = 100 μm (A) and 50 μm (B and C).
- FIGURE 5.
Photomicrographs of fluorescence immunohistochemistry against GLUT1 in periinfarct neocortex of vehicle- (A) and BMSC-transplanted animals (B). Scale bars = 200 μm.
- FIGURE 6.
(A) Photomicrographs of double immunohistochemistry against GLUT3 (red) and NeuN (green) in contralateral neocortex of vehicle-transplanted animals. Subgroup of NeuN-positive cells was also positive for GLUT3. Scale bars = 100 μm. (B and C) Photomicrographs of fluorescence immunohistochemistry against GLUT3 in ipsilateral neocortex of vehicle- (A) and BMSC-transplanted animals (B). Scale bars = 200 μm. Ipsilat = ipsilateral neocortex.
