FDG PET/CT utility in gynecologic malignancies: A comprehensive interactive review of anatomy, pathways of metastatic spread and scan findings

Learning Objectives 1. Pictoral review of clinical features of major gynecologic cancers including cervical, ovarian, uterine, vaginal, and vulva malignancies and demonstrate the role of FDG PET/CT. 2. Illustrate and correlate anatomic and conventional imaging features of gynecologic malignancies. 3. Demonstrate the integration of FIGO scoring and treatment planning to improve accuracy of staging.

In the United States in 2007,* 80,976 women were diagnosed with gynecologic cancer, and 27,739 succumbed to the disease. Our objective was to review the five major gynecologic cancers (cervical, ovarian, uterine, vaginal, and vulvar) and demonstrate the role of FDG PET/CT in diagnosis, surveillance, FIGO staging and treatment strategy. Approximately 15,000 FDG whole body PET/CT cases were done at Emory University over the past 5 years. We selected FDG PET/CT cases with strong key representative findings for each of these gynecological cancers for presentation. The FIGO staging, treatment strategy, correlative imaging and lab results were reviewed in each case presented. In addition, FDG PET/CT imaging of other rare as well as unusual presentations of major gynecological cancers will be touched upon. Understanding of key findings in gynecological malignancies is crucial for early diagnosis, treatment strategy and assessment of treatment response. The viewer will be asked to identify anatomic landmarks, pathologic findings and staging at the end of the interactive presentation