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Journal of Nuclear Medicine

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Meeting ReportTechnologist Abstracts

3D-OSEM vs FORE+OSEM: The optimal reconstruction algorithm in FDG PET tests with short acquisition time

Keisuke Tsuda, Masahiro Fukushi, Akira Hirayama, Takayuki Suzuki, Kazuhito Toya, Kazuya Koyama, Yuto Iwabuchi, Koichi Nemoto, Noriyuki Moriyama and Hirofumi Fujii
Journal of Nuclear Medicine May 2011, 52 (supplement 1) 2371;
Keisuke Tsuda
1National Cancer Center, Tokyo, Japan
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Masahiro Fukushi
2Tokyo Metropolitan University, Tokyo, Japan
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Akira Hirayama
3GE Japan, Tokyo, Japan
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Takayuki Suzuki
4Toto Clinic, Tokyo, Japan
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Kazuhito Toya
5Tokyo Medical Center, Tokyo, Japan
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Kazuya Koyama
1National Cancer Center, Tokyo, Japan
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Yuto Iwabuchi
1National Cancer Center, Tokyo, Japan
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Koichi Nemoto
1National Cancer Center, Tokyo, Japan
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Noriyuki Moriyama
1National Cancer Center, Tokyo, Japan
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Hirofumi Fujii
1National Cancer Center, Tokyo, Japan
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Abstract

2371

Objectives To determine the optimal reconstruction algorithm in FDG PET tests with short acquisition time (SAT).

Methods In phantom studies, an NEMA phantom with 6 spheres filled with FDG (sphere size: 6.23-37 mm; radioactivity ratio of spheres to background = 8:1) was evaluated. Image acquisition time was varied between 15 and 180 s, and obtained image data were reconstructed using both FORE+OSEM and 3D-OSEM algorithms. Further, in clinical studies, 19 cases of mid-abdominal images were evaluated by putting 3 kinds of ROIs having different counts. All obtained images were investigated visually as well as quantitatively, using SUV and coefficient of variation (CV).

Results In phantom studies, FORE+OSEM images with SAT showed large CVs (poor image quality) whereas SUVs were comparatively constant. 3D-OSEM images showed comparatively constant CVs (good image quality) whereas SUVs had significantly decreased. The results of visual evaluation were well correlated with those of quantitative evaluation. Small spheres were obscured on 3D-OSEM images with SAT although their image quality was not greatly deteriorated. Clinical studies yielded results similar to phantom examinations.

Conclusions FDG PET images with SAT reconstructed by FORE+OSEM showed poor image quality whereas images reconstructed by 3D-OSEM showed obscured uptake. FORE+OSEM reconstruction might be useful under SAT because FORE+OSEM images showed clear FDG uptakes, which can be identified by comparing them with simultaneously obtained CT images

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Results of phantom study

*: statistically significant

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Journal of Nuclear Medicine
Vol. 52, Issue supplement 1
May 2011
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3D-OSEM vs FORE+OSEM: The optimal reconstruction algorithm in FDG PET tests with short acquisition time
Keisuke Tsuda, Masahiro Fukushi, Akira Hirayama, Takayuki Suzuki, Kazuhito Toya, Kazuya Koyama, Yuto Iwabuchi, Koichi Nemoto, Noriyuki Moriyama, Hirofumi Fujii
Journal of Nuclear Medicine May 2011, 52 (supplement 1) 2371;

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3D-OSEM vs FORE+OSEM: The optimal reconstruction algorithm in FDG PET tests with short acquisition time
Keisuke Tsuda, Masahiro Fukushi, Akira Hirayama, Takayuki Suzuki, Kazuhito Toya, Kazuya Koyama, Yuto Iwabuchi, Koichi Nemoto, Noriyuki Moriyama, Hirofumi Fujii
Journal of Nuclear Medicine May 2011, 52 (supplement 1) 2371;
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