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Journal of Nuclear Medicine

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Research ArticleBrief Communication

SPECT/CT and a Portable γ-Camera for Image-Guided Laparoscopic Sentinel Node Biopsy in Testicular Cancer

Oscar R. Brouwer, Renato A. Valdés Olmos, Lenka Vermeeren, Cornelis A. Hoefnagel, Omgo E. Nieweg and Simon Horenblas
Journal of Nuclear Medicine April 2011, 52 (4) 551-554; DOI: https://doi.org/10.2967/jnumed.110.086660
Oscar R. Brouwer
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Renato A. Valdés Olmos
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Lenka Vermeeren
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Cornelis A. Hoefnagel
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Omgo E. Nieweg
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Simon Horenblas
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  • FIGURE 1.
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    FIGURE 1.

    (A) Planar anterior image showing drainage of 99mTc-nanocolloid from injection site in right testicle to 2 abdominal lymph nodes and radioactivity along lymphatic channel, which decreased in time, indicating lymphatic tract visualization. (B) Coronal SPECT/CT image fusion showing both sentinel lymph nodes (yellow) alongside inferior vena cava. (C) Laparoscopic SN procedure using portable γ-camera and laparoscopic γ-ray detection probe. (D) Preexcision image (left screen) acquired with portable γ-camera showing both SNs in operation room. After excision (right screen), no significant remaining activity is seen.

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    FIGURE 2.

    (A) Planar anterior image showing drainage from right testicle to 2 adjacent lymph nodes in medial area of abdomen. Some uptake is also seen in more laterally located lymph node (arrows). (B) Coronal fused SPECT/CT image showing both medial lymph nodes between aorta and vena cava and lateral node in trajectory of right testicular vessels. (C) Transverse SPECT/CT image showing 2 SNs displayed in yellow. (D) CT image showing that medial SN corresponds to small lymph node ventral to area between aorta and cava, whereas lateral node is in area ventral to psoas muscle (circles). In this funicular SN, micrometastases were found at histopathology.

  • FIGURE 3.
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    FIGURE 3.

    (A) Planar anterior image showing drainage from injection site in left testicle to 2 abdominal lymph nodes (arrows) and radioactivity along lymphatic channel indicating lymphatic tract visualization. (B) Fused SPECT/CT image displayed with 3-dimensional volume rendering showing cranial lymph node alongside aorta and caudal node in retroperitoneal trajectory of left testicular vessels (arrows). Some remaining activity is seen in lymphatic channels. (C) Transversal fused SPECT/CT image showing caudal SN (displayed in yellow). (D) CT image showing corresponding lymph node ventral from left psoas muscle (within circle). (E and F) Paraaortic SN is displayed in both fused SPECT/CT (yellow on E) image and CT (within circle on F) image.

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    TABLE 1

    Patient Characteristics and SN Results

    PatientAge (y)SidePathologySPECT/CT findingsExcised nodesSN metastasesRecurrenceFollow-up (mo)
    150LeftSeminoma1 SN, paraaortic zone1——50
    229RightSeminoma1 SN, paracaval zone4——46
    1 SN, interaortocaval zone
    334RightSeminoma2 SNs, interaortocaval zone2——39
    433LeftSeminoma2 SNs, paraaortic zone4——39
    534RightNonseminoma2 SNs, interaortocaval zone3——23
    1 SN, right common iliac zone
    641LeftSeminoma1 SN, paraaortic zone1——19
    748RightSeminoma2 SNs, interaortocaval zone3+—11
    1 SN, adjacent to (right) testicular vessels
    837RightSeminoma2 SNs, paracaval zone2——6
    935LeftSeminoma1 SN, paraaortic zone3——6
    1 SN, adjacent to (left) testicular vessels
    1025LeftNonseminoma2 SNs, paraaortic zone3——2
    1 SN, adjacent to (left) testicular vessels
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Journal of Nuclear Medicine: 52 (4)
Journal of Nuclear Medicine
Vol. 52, Issue 4
April 1, 2011
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SPECT/CT and a Portable γ-Camera for Image-Guided Laparoscopic Sentinel Node Biopsy in Testicular Cancer
Oscar R. Brouwer, Renato A. Valdés Olmos, Lenka Vermeeren, Cornelis A. Hoefnagel, Omgo E. Nieweg, Simon Horenblas
Journal of Nuclear Medicine Apr 2011, 52 (4) 551-554; DOI: 10.2967/jnumed.110.086660

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SPECT/CT and a Portable γ-Camera for Image-Guided Laparoscopic Sentinel Node Biopsy in Testicular Cancer
Oscar R. Brouwer, Renato A. Valdés Olmos, Lenka Vermeeren, Cornelis A. Hoefnagel, Omgo E. Nieweg, Simon Horenblas
Journal of Nuclear Medicine Apr 2011, 52 (4) 551-554; DOI: 10.2967/jnumed.110.086660
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