A comparison of digital autoradiography and composite fluorescence images of tumor hypoxia and vasculature. In a study evaluating the ability of ¹⁸F-fluoromisonidazole PET to monitor tumor response to an antivascular compound, the pattern of the tracer uptake reflected the effect of the compound on tumor physiology. ¹⁸F-fluoromisonidazole distribution was found to be governed by tumor tracer delivery as well as locoregional tumor hypoxia.
See page 437.