¹⁸F-FLT uptake can be used to monitor the biologic response of esophageal squamous cell carcinoma to radiotherapy and may have an advantage over ¹⁸F-FDG in differentiating inflammation from tumor. Increased uptake of ¹⁸F-FLT after treatment interruption, as occurred in the patient shown here, may reflect accelerated repopulation. After the interruption, tumoral uptake rose above baseline whereas uptake in irradiated bone marrow decreased.
See page 528.