¹⁸F-FET PET and ¹H MRSI provide insight into metabolic changes related to pathologic processes. Coregistration of data from these techniques with MRI data allows direct correlation of changes in amino acid uptake with changes in membrane, energy, and neuronal metabolism. The 2 metabolic imaging methods have been shown to provide complementary information on glioma metabolism that may be useful in planning and targeting surgery and radiochemotherapy.
See page 721.