Article Figures & Data
Figures
- FIGURE 1.
99mTc-Tetrofosmin SPECT and 18F-FDG PET studies (bull's-eye view and representative vertical long-axis and short-axis slices) of patient after recanalization of totally occluded left anterior descending coronary artery (baseline) and 3 mo after administration of CPCs (follow-up). Arrows indicate area with reduced 99mTc-tetrofosmin and enhanced 18F-FDG uptake corresponding to perfusion–metabolism mismatch in anterolateral area at baseline (arrows) and disappearance of this finding at follow-up.
- FIGURE 2.
99mTc-Tetrofosmin SPECT and 18F-FDG PET studies (bull's-eye view and representative vertical long-axis and short-axis slices) of patient after recanalization of totally occluded right coronary artery (baseline) and 3 mo after administration of cell-free serum (follow-up). Arrows indicate area with reduced 99mTc-tetrofosmin and enhanced 18F-FDG uptake corresponding to perfusion–metabolism mismatch in posteroseptal area at baseline. In this area, slight deterioration in perfusion occurs at follow-up.
- FIGURE 3.
Three-month follow-up of segments classified as normal (A) or having perfusion–metabolism (p/m) mismatch (B) within area of total coronary occlusion (target area) at 8 ± 1 d after recanalization. For both situations, group differences were significant (P < 0.05, χ2 test).
- FIGURE 4.
Change in number of segments classified as scar, perfusion–metabolism (p/m) mismatch, or normal in each patient from baseline to follow-up, for CPC group (A) and placebo group (B). Each patient is represented by 1 line. In most CPC patients, normal segments increase and segments with perfusion–metabolism mismatch decrease. Table 1 provides the statistics.
Tables
Placebo group CPC group Segment type Baseline Follow-up P Baseline Follow-up P Normal 3.7 (0.9) 3.0 (0.8) NS 3.4 (0.5) 5.2 (0.9) 0.015 Mismatch 2.7 (0.6) 3.6 (0.6) NS 3.0 (0.5) 1.7 (0.6) 0.048 Scar 1.0 (0.4) 0.8 (0.5) NS 1.8 (0.5) 1.3 (0.6) NS NS = not statistically significant.
Significance testing between baseline and follow-up was done on per-patient base by Wilcoxon rank test. Data in parentheses are SE of mean.
