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Journal of Nuclear Medicine

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OtherCONTINUING EDUCATION

Treatment of Thyrotoxicosis

Andrei Iagaru and I. Ross McDougall
Journal of Nuclear Medicine March 2007, 48 (3) 379-389;
Andrei Iagaru
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I. Ross McDougall
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    TABLE 1

    Symptoms and Signs of Thyrotoxicosis

    SymptomsSigns
    Weight lossTachycardia
    NervousnessSweatiness
    PalpitationsFeeling hot
    Feeling hot or sweatinessFine tremor
    Loose bowel movementsAtrial fibrillation
    Poor staminaRestlessness
    BreathlessnessApathy (older people)
    TremulousnessWeight loss
    Poor concentrationGoiter*
    ChangesEye signs*
    Pretibial* dermopathy
    Finger clubbing*
    • ↵* Features specific to Graves' disease.

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    TABLE 2

    Causes of Thyrotoxicosis

    High uptake of iodineLow uptake of iodine
    Graves' disease (Basedow's disease)Exogenous thyroid hormone
    Functioning noduleMedicamentous
    Toxic multinodular goiterFactitious
    Pituitary tumor secreting excess TSH Dietary (hamburger thyrotoxicosis)
    Tumors of placenta secreting large quantities of human chorionic gonadotropinThyroiditis
     Subacute
     Silent
     Postpartum
    Excess iodine
    Jodbasedow
    Amiodarone
    Uptake at other sites, struma ovarii, functioning thyroid metastases
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Journal of Nuclear Medicine: 48 (3)
Journal of Nuclear Medicine
Vol. 48, Issue 3
March 2007
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Treatment of Thyrotoxicosis
Andrei Iagaru, I. Ross McDougall
Journal of Nuclear Medicine Mar 2007, 48 (3) 379-389;

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Treatment of Thyrotoxicosis
Andrei Iagaru, I. Ross McDougall
Journal of Nuclear Medicine Mar 2007, 48 (3) 379-389;
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  • Article
    • Abstract
    • DIAGNOSTIC TESTING
    • TREATMENT OF GRAVES' DISEASE
    • ANTITHYROID MEDICATIONS
    • SURGERY
    • HISTORICAL BACKGROUND FOR 131I TREATMENT
    • GOAL OF TREATMENT
    • HOW IS ADMINISTERED DOSE DETERMINED?
    • CALCULATING ADMINISTERED DOSE
    • CALCULATING ABSORBED DOSE
    • SELECTION OF DOSE OF 131I IN PRACTICE
    • ALTERNATIVE RADIONUCLIDES OF IODINE
    • FAILURE OF THERAPY
    • TREATMENT OF SINGLE HYPERFUNCTIONING AUTONOMOUS NODULE
    • TOXIC MULTINODULAR GOITERS
    • SIDE EFFECTS AND COMPLICATIONS
    • LITHIUM AS ADJUVANT TO 131I
    • RADIATION SAFETY
    • AIRPORT SECURITY AND 131I TREATMENT
    • SPECIAL SITUATIONS
    • CONCLUSION
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • PDF

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