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Hepatocellular carcinomas have different glucose-regulating mechanisms from those of cholangiocarcinomas, even though both tumors show increased 18F-FDG uptake on PET scans. Hepatocellular carcinomas stain negatively for Glut 1 but positively for HK II. Cholangiocarcinomas stain positively for Glut 1 but negatively for HK II.
SEE PAGE 1753.