ON THE COVER

In these autoradiographs of heart slices from male Wistar rats, ^99mTc-Annexin V shows the area of and intensity of apoptosis and ²⁰¹Tl shows the area at risk. ^99mTc-annexin V uptake was significant in the area at risk and decreased with time after reperfusion. Significant uptake of ^99mTc-annexin V is seen predominantly in the mid myocardium at 0.5 and 1.5 h after reperfusion and expands to the subendomyocardial and subepicardial layers and lateral border zone of ischemia at 6 h after reperfusion. Annexin V uptake is still observed after 1 d of reperfusion and decreases during the 3 d after reperfusion.