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Journal of Nuclear Medicine

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OtherClinical Investigations

123I-Metaiodobenzylguanidine Myocardial Scintigraphy in Panic Disorder

Yoshio Tanabe, Hiromi Harada, Shuji Sugihara, Toshihide Ogawa and Yuichi Inoue
Journal of Nuclear Medicine August 2004, 45 (8) 1305-1308;
Yoshio Tanabe
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Hiromi Harada
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Shuji Sugihara
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Toshihide Ogawa
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Yuichi Inoue
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    FIGURE 1.

    Myocardial 123I-MIBG anterior planar images (30 min [early image, left] and 4 h [delayed image, right]) of 52-y-old healthy control subject, with early H/M ratio of 2.31, delayed H/M ratio of 2.51, and WR of 26.1% (A) and of 39-y-old man with panic disorder (patient 3), with early H/M ratio of 1.63, delayed H/M ratio of 1.61, and WR of 36.1% (B).

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    TABLE 1

    Patient Characteristics

    Patient no.Age (y)SexDisease duration (y)Disease severity (stage)Drug therapy (daily dose)Drug cessation period* (d)
    116F3.25Alprazolam (1.6 mg)5
    254M5.84Alprazolam (0.8 mg)11
    339M6.34Alprazolam (1.2 mg)6
    437M4.95—
    530M5.12Alprazolam (1.2 mg)3
    639F6.27Alprazolam (2.4 mg)3
    731M3.85—
    860M4.44Alprazolam (0.8 mg)3
    931M8.44Alprazolam (0.8 mg)5
    • ↵* Days before 123I-MIBG examination.

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    TABLE 2

    Comparison of Scintigraphic Parameters of 123I-MIBG

    ParameterPatientsHealthy control subjectsP
    Myocardial uptake
        Early1.80 ± 0.162.15 ± 0.150.001
        Late1.86 ± 0.302.26 ± 0.210.009
    WR myocardium33.8% ± 6.9%27.8% ± 3.5%0.02
    • Data are expressed as mean ± SD. Uptake was measured by H/M ratio.

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Journal of Nuclear Medicine: 45 (8)
Journal of Nuclear Medicine
Vol. 45, Issue 8
August 1, 2004
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123I-Metaiodobenzylguanidine Myocardial Scintigraphy in Panic Disorder
Yoshio Tanabe, Hiromi Harada, Shuji Sugihara, Toshihide Ogawa, Yuichi Inoue
Journal of Nuclear Medicine Aug 2004, 45 (8) 1305-1308;

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123I-Metaiodobenzylguanidine Myocardial Scintigraphy in Panic Disorder
Yoshio Tanabe, Hiromi Harada, Shuji Sugihara, Toshihide Ogawa, Yuichi Inoue
Journal of Nuclear Medicine Aug 2004, 45 (8) 1305-1308;
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