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Journal of Nuclear Medicine

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OtherClinical Investigations

Preparation of Patients with Thyroid Cancer for 131I Scintigraphy or Therapy by 1–3 Weeks of Thyroxine Discontinuation

Perry W. Grigsby, Barry A. Siegel, Simon Bekker, William E. Clutter and Jeffrey F. Moley
Journal of Nuclear Medicine April 2004, 45 (4) 567-570;
Perry W. Grigsby
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Barry A. Siegel
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Simon Bekker
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William E. Clutter
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Jeffrey F. Moley
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  • FIGURE 1.
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    FIGURE 1.

    (A) Scatter plot of first TSH measurements as a function of time after total thyroidectomy (n = 176). (B) Cumulative frequency of TSH concentrations > 30 μIU/mL as a function of time after total thyroidectomy (n = 176).

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    FIGURE 2.

    (A) Scatter plot of first TSH measurements as a function of time after abrupt T4 withdrawal (n = 108). (B) Cumulative frequency of TSH concentrations > 30 μIU/mL as a function of time after abrupt T4 withdrawal (n = 108).

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    TABLE 1

    Postoperative TSH Levels by Time Period

    Time after surgery (d)No. of patientsNo. with TSH > 30 μIU/mL
    7–144641 (89%) [77%–95%]
    15–218070 (88%) [79%–93%]
    >215045 (90%) [79%–96%]
    Total176156 (89%) [84%–93%]
    • Ranges in brackets are 95% confidence intervals.

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    TABLE 2

    TSH Levels by Time After Abrupt T4 Withdrawal

    Time after withdrawal (d)No. of patientsNo. with TSH > 30 μIU/mL
    7–1477 (100%) [65%–100%]
    15–215448 (89%) [78%–95%]
    >214745 (96%) [86%–99%]
    Total108100 (93%) [86%–97%]
    • Ranges in brackets are 95% confidence intervals.

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Journal of Nuclear Medicine: 45 (4)
Journal of Nuclear Medicine
Vol. 45, Issue 4
April 1, 2004
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Preparation of Patients with Thyroid Cancer for 131I Scintigraphy or Therapy by 1–3 Weeks of Thyroxine Discontinuation
Perry W. Grigsby, Barry A. Siegel, Simon Bekker, William E. Clutter, Jeffrey F. Moley
Journal of Nuclear Medicine Apr 2004, 45 (4) 567-570;

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Preparation of Patients with Thyroid Cancer for 131I Scintigraphy or Therapy by 1–3 Weeks of Thyroxine Discontinuation
Perry W. Grigsby, Barry A. Siegel, Simon Bekker, William E. Clutter, Jeffrey F. Moley
Journal of Nuclear Medicine Apr 2004, 45 (4) 567-570;
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Cited By...

  • SNMMI Procedure Standard/EANM Practice Guideline for Nuclear Medicine Evaluation and Therapy of Differentiated Thyroid Cancer: Abbreviated Version
  • The SNMMI Practice Guideline for Therapy of Thyroid Disease with 131I 3.0
  • A New Age for Recombinant Human Thyroid-Stimulating Hormone?
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