Article Figures & Data
Figures
- FIGURE 1.
Glioblastoma multiforme of right frontotemporal region, revealed on T1-weighted MRI with gadolinium (A) and T2-weighted MRI (B), is also well defined on sestamibi scan (C).
- FIGURE 2.
Serial pairings of sagittal MRI and SPECT images for 15-y-old boy with exophytic brain stem glioma. Third column is black-and-white version of original SPECT images. Baseline images (A) are compared with scans at 8 (B) and 12 (C) mo, both of which show increased signal on 99mTc-MIBI SPECT but no change on MRI. Final panel (D) demonstrates increased tumor on MRI at 16 mo, accompanied by decreased signal from SPECT.
Tables
Patient no. Age (y) Sex Tumor Location 1 6 M Brain stem glioma Midbrain 2 9 F Brain stem glioma Midbrain 3 15 M Brain stem glioma Midbrain 4 8 M Brain stem glioma Midbrain 5 5 M Brain stem glioma Midbrain 6 9 F Brain stem glioma Pons 7 14 M Brain stem glioma Pons 8 7 F Brain stem glioma Pons 9 13 F Glioblastoma multiforme Frontoparietal 10 11 M Glioblastoma multiforme Parietal lobe 11 17 M Astrocytoma (low) Temporal 12 9 M Astrocytoma (pilocytic) Parietal 13 12 F Astrocytoma (pilocytic) Thalamus 14 10 M Spinal astrocytoma Cervical spine (C2–C4) 15 5 M Dysembryoplastic neuroepithelial tumor Temporal lobe 16 5 F Medulloblastoma Medulla/4th ventricle 17 15 M Craniopharyngioma Pituitary gland 18 9 F Optic glioma Optic chiasm 19 17 F Choroid plexus carcinoma Lateral ventricle 20 8 M Ependymoma Medulla/4th ventricle Patient no. Diagnosis Grade 99mTc-MIBI imaging MRI 1 Brain stem glioma I − ++ 2 Brain stem glioma II ++ ++ 3 Brain stem glioma II ++ ++ Brain stem glioma II ++ + Brain stem glioma II ++ ++ Brain stem glioma II ++ ++ 4 Brain stem glioma NA − + 5 Brain stem glioma II − ++ 6 Brain stem glioma NA ++ ++ Brain stem glioma NA ++ ++ 7 Brain stem glioma NA ++ ++ 8 Brain stem glioma NA ++ ++ 9 Glioblastoma multiforme IV ++ + 10 Glioblastoma multiforme IV − + Glioblastoma multiforme IV ++ + Glioblastoma multiforme IV − − 11 Astrocytoma II − ++ 12 Astrocytoma (pilocytic) II − − Astrocytoma (pilocytic) II − + 13 Astrocytoma (pilocytic) I ++ ++ 14 Spinal astrocytoma III − ++ Spinal astrocytoma III − ++ 15 Desembryoplastic neuroepithelial tumor I − + 16 Medulloblastoma IV − ++ 17 Craniopharyngioma I − ++ 18 Optic glioma II − ++ 19 Choroid plexus carcinoma III ++ + Choroid plexus carcinoma III − − 20 Ependymoma II − + − = no evidence of tumor; ++ = definitive tumor; + = suggestive tumor; NA = not applicable.
Patient no. Time (mo) 99mTc-MIBI MRI Progression 3 0 + + 8 +I +NC No 12 +I +NC No 16 +D +I No 10 0 − + 3 + +NC No 6 − − Yes 14 0 − + 6 − +NC Yes 6 0 + + 6 +I +I Yes 12 0 − − 14 − + Yes 19 0 + + 16 − − No + = tumor evident; +I = increased tumor from previous image; +NC = no change in tumor from previous image; +D = decreased tumor from previous image; − = no evidence of tumor.
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