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Journal of Nuclear Medicine

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OtherBasic Science Investigations

110mIn-DTPA-d-Phe1-Octreotide for Imaging of Neuroendocrine Tumors with PET

Mark Lubberink, Vladimir Tolmachev, Charles Widström, Alexander Bruskin, Hans Lundqvist and Jan-Erik Westlin
Journal of Nuclear Medicine October 2002, 43 (10) 1391-1397;
Mark Lubberink
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Vladimir Tolmachev
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Charles Widström
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Alexander Bruskin
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Hans Lundqvist
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Jan-Erik Westlin
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  • FIGURE 1.
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    FIGURE 1.

    Spatial resolution in PET and SPECT with 110mIn and 111In, respectively. Just outside FOV in SPECT measurement was 20-cm point. FWHM = full width at half maximum.

  • FIGURE 2.
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    FIGURE 2.

    Sphere recovery functions for 110mIn PET, 111In SPECT, and 18F PET.

  • FIGURE 3.
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    FIGURE 3.

    Reoriented reconstructed SPECT images 24 h after administration of 175 MBq of 111In-octreotide. Rectangles indicate position of PET images in Figure 4.

  • FIGURE 4.
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    FIGURE 4.

    Reoriented PET images of same patient as in Figure 3, 1.5 h after administration of 110mIn-octreotide.

  • FIGURE 5.
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    FIGURE 5.

    Standard uptake values of 110mIn-octreotide in tumor, background tissue, blood, and kidney. Error bars are of same size as markers.

Tables

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    TABLE 1

    Main Decay Radiation of 110mIn and 111In

    IsotopeHalf-lifeRadiationEnergy (keV)Abundance (%)
    111In2.8 dγ245.494
    171.390.2
    Auger2.7298
    19.315.6
    Conversion electrons144.67.8
    X-ray23.244.3
    23.023.5
    26.114.5
    110mIn69.1 minβ+, total1,010 (maximum, 2,260)62
    γ657.898
    Auger2.7233.5
    19.35.3
    X-ray23.215
    23.08
    • Data are for positrons, γ-radiation, Auger and conversion electrons, and x-rays with abundances > 5%.

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Journal of Nuclear Medicine: 43 (10)
Journal of Nuclear Medicine
Vol. 43, Issue 10
October 1, 2002
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110mIn-DTPA-d-Phe1-Octreotide for Imaging of Neuroendocrine Tumors with PET
Mark Lubberink, Vladimir Tolmachev, Charles Widström, Alexander Bruskin, Hans Lundqvist, Jan-Erik Westlin
Journal of Nuclear Medicine Oct 2002, 43 (10) 1391-1397;

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110mIn-DTPA-d-Phe1-Octreotide for Imaging of Neuroendocrine Tumors with PET
Mark Lubberink, Vladimir Tolmachev, Charles Widström, Alexander Bruskin, Hans Lundqvist, Jan-Erik Westlin
Journal of Nuclear Medicine Oct 2002, 43 (10) 1391-1397;
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