Article Figures & Data
Figures
- FIGURE 1.
Schematic diagram of 4 study groups. ARG = autoradiography.
- FIGURE 2.
H- and E-stained sections from paraffin blocks show changes in tumor histology for groups 1–4. Radiation was delivered in 5 2-Gy fractions on days 0–4. (A) Group 1 (control), ×100 magnification. (B) Group 2 (day 5 after initiation of radiation therapy), ×100 magnification. (C) Group 3 (day 10 after initiation of radiation therapy), ×200 magnification. (D) Group 4 (day 15 after initiation of radiation therapy), ×100 magnification.
- FIGURE 3.
Immunoperoxidase- and H- and E-stained frozen sections show changes in tumor histology for groups 1–4. (A) Group 1 (control), ×100 magnification. (B) Group 2 (day 5 after initiation of radiation therapy), ×200 magnification. (C) Group 3 (day 10 after initiation of radiation therapy), ×100 magnification. (D) Group 4 (day 15 after initiation of radiation therapy), ×100 magnification.
- FIGURE 4.
Digital phosphor plate autoradiographs from frozen tissue sections. Two sections (from 2 different tumors) for each study group (A, group 1; B, group 2; C, group 3; D, group 4) illustrate changes in antibody distribution. (A–D) Same magnification.
Tables
- TABLE 1.
Measurements of Cell Number and Fraction That Stained Positive for A33 Antigen on Frozen Tissue Sections for 4 Study Groups
Group Cell no./mm2 % Antigen positive 1 (day 0, no XRT) 5550 85.2 2 (day 5, XRT days 1–5) 4115 64.4 3 (day 10, XRT days 1–5) 3190 50.4 4 (day 15, XRT days 1–5) 2910 41.3 Group %ID/g tumor ± SD 1 (day 0, no XRT) 10.3 ± 6.1 2 (day 5, XRT days 1–5) 15.1 ± 6.3 3 (day 10, XRT days 1–5) 9.2 ± 7.5 4 (day 15, XRT days 1–5) 2.2 ± 0.3
