Syngeneic mouse model

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Mesothelin/CD3 half-life extended bispecific T-cell engager molecule shows specific tumor uptake and distributes to mesothelin and CD3 expressing tissues
Frans V Suurs, Grit Lorenczewski, Julie M Bailis, Sabine Stienen, Matthias Friedrich, Fei Lee, Bert van der Vegt, Elisabeth G.E. de Vries, Derk-Jan A. de Groot and Marjolijn N Lub - de Hooge

Journal of Nuclear Medicine April 30, 2021, jnumed.120.259036; DOI: https://doi.org/10.2967/jnumed.120.259036
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Immune-Checkpoint Blockade Enhances ²²⁵Ac-PSMA617 Efficacy in a Mouse Model of Prostate Cancer
Johannes Czernin, Kyle Current, Christine E. Mona, Lea Nyiranshuti, Firas Hikmat, Caius G. Radu and Katharina Lückerath

Journal of Nuclear Medicine February 1, 2021, 62 (2) 228-231; DOI: https://doi.org/10.2967/jnumed.120.246041
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The Biodistribution of a CD3 and EpCAM Bispecific T-Cell Engager Is Driven by the CD3 Arm
Frans V. Suurs, Grit Lorenczewski, Sabine Stienen, Matthias Friedrich, Elisabeth G.E. de Vries, Derk Jan A. de Groot and Marjolijn N. Lub-de Hooge

Journal of Nuclear Medicine November 1, 2020, 61 (11) 1594-1601; DOI: https://doi.org/10.2967/jnumed.120.241877

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