Elevated expression of the c-Met receptor plays a crucial role in cancers. In non–small cell
lung cancer (NSCLC), aberrant activation of the c-Met signaling pathway contributes to …

Objectives c-Met is a receptor tyrosine kinase shown inappropriate expression and actively
involved in progression and metastasis in most types of human cancer. Development of c …

Non–small cell lung cancer (NSCLC) is a difficult disease to treat. The c-Met receptor is an
attractive potential target for novel therapeutic inhibition in human cancers. We provide …

c-Met is a receptor tyrosine kinase involved in tumor cell growth, invasion, metastases and
angiogenesis. Overexpression of c-Met is frequently observed in several tumor types. Here …

Background The c-met receptor and its ligand hepatocyte growth factor have been shown to
be involved in tumor invasiveness and metastasis. Overexpression of c-met has been …

Abstract Purpose: Aberrant c-Met expression has been implicated in most types of human
cancer. We are developing Met-directed imaging and therapeutic agents. Experimental …

Background Immunohistochemistry (IHC) and fluorescent in situ hybridization are reliable
methods for identifying c-Met protein expression or c-Met gene amplification. However, each …

Introduction: The radiation doses used to treat unresectable lung cancer are often limited by
the proximity of normal tissues. Overexpression of c-Met, a receptor tyrosine kinase, occurs …

Objective A novel 99mTc‐tricine‐EDDA‐Hynic‐c‐Met molecular probe was synthetized, and
nude mice models of human non‐small‐cell lung cancer (NSCLC) were established in order …

Objective: The aim of this study is to reveal the correlation of shedding and expression of c-
Met in non-small cell lung cancer (NSCLC) patient. Materials and methods: We measured …