The NK-drived exosomes enhance NK cell-based therapy to melanoma cancer

Z Liya, S Kalimuthu, P Gangadaran, J Oh, SH Baek… - 2016 - Soc Nuclear Med
1393 Objectives Exosomes are nanovesicles released by normal and tumor cells, which are
detectable in cell culture supernatant and human biological fluids, such as plasma …

[HTML][HTML] Exosomes derived from natural killer cells exert therapeutic effect in melanoma

L Zhu, S Kalimuthu, P Gangadaran, JM Oh, HW Lee… - Theranostics, 2017 - ncbi.nlm.nih.gov
Objective: Exosomes are nanovesicles that are released from normal and tumor cells and
are detectable in cell culture supernatant and human biological fluids. Although previous …

[HTML][HTML] Anti-leukemia effects of NK cell-derived exosomes

M Boyiadzis, CS Hong, TL Whiteside - Blood, 2019 - Elsevier
Introduction: Exosomes are 30-150 nm-sized extracellular vesicles originating from the
endocytic compartment of parent cells. The exosome molecular cargo reflects the content of …

[HTML][HTML] Uptake characterization of tumor cell-derived exosomes by natural killer cells

T Huyan, DU Yongyong, Q Huang… - Iranian Journal of …, 2018 - ncbi.nlm.nih.gov
Background: Cancer is the leading cause of death in human disease and is a major public
health problem around the world. Exosomes are a promising cancer biomarker and therapy …

Immune surveillance properties of human NK cell-derived exosomes

L Lugini, S Cecchetti, V Huber, F Luciani… - The Journal of …, 2012 - journals.aai.org
Exosomes are nanovesicles released by normal and tumor cells, which are detectable in
cell culture supernatant and human biological fluids, such as plasma. Functions of …

[HTML][HTML] Using NK-derived exosomes to treat leukemia

A Samara, G Granot, M Anbar, P Raanani, U Rozovski - Blood, 2021 - Elsevier
Natural killer cells (NK) are components of the innate immune system which play an
important role in surveillance of cancer cells. Despite promising results in clinical trials, the …

[HTML][HTML] Bioactivity of exosomes derived from trained natural killer cells versus non-trained one: more functional and antitumor activity

F Mohammadi, ZS Hashemi, RS Forooshani… - BioMed Research …, 2022 - hindawi.com
Background. Natural killer (NK) cells are cytotoxic lymphocytes of the innate immune system,
capable of killing viral-infected and cancerous cells. NK cell-mediated immunotherapy has …

[HTML][HTML] The interplay of exosomes and NK cells in cancer biology

IA Batista, ST Quintas, SA Melo - Cancers, 2021 - mdpi.com
Simple Summary Cancer is a lethal disease and the second most common cause of death
worldwide. It is estimated that the next decades will bring a rise of about 50% in cancer …

[HTML][HTML] Large-scale Isolation of Exosomes Derived from NK Cells for Anti-tumor Therapy

H Luo, J Zhang, A Yang, W Ouyang, S Long, X Lin… - Bio …, 2023 - ncbi.nlm.nih.gov
Exosomes are lipid bilayer–enclosed vesicles, actively secreted by cells, containing
proteins, lipids, nucleic acids, and other substances with multiple biological functions after …

[HTML][HTML] Hypoxia enhances the production and antitumor effect of exosomes derived from natural killer cells

Y Jiang, H Jiang, K Wang, C Liu, X Man… - Annals of Translational …, 2021 - ncbi.nlm.nih.gov
Background Exosomes are a subgroup of extracellular vesicles that are naturally released
by almost all types of cells. However, the factors that promote the capacity of natural killer …