Linear versus nonlinear regression for quantification of dynamic PET with amphetamine challenge
546 Objectives: To evaluate a linear regression algorithm for the quantification of dynamic
PET with amphetamine challenge using an improved ESRTM model. Methods: Sixteen …
PET with amphetamine challenge using an improved ESRTM model. Methods: Sixteen …
An extended simplified reference tissue model for the quantification of dynamic PET with amphetamine challenge
BACKGROUND:: Equilibrium analysis to quantify dynamic positron emission tomography
(PET) with bolus followed by continuous tracer infusion and acute amphetamine challenge …
(PET) with bolus followed by continuous tracer infusion and acute amphetamine challenge …
A non-invasive approach to measure the latent period in the amphetamine-induced displacement of [11C] raclopride using single dynamic PET with bolus plus …
1114 Objectives: To non-invasively measure the latent period in the amphetamine-induced
displacement of [11 C] raclopride. Methods: Twenty six cynomologous monkeys and six …
displacement of [11 C] raclopride. Methods: Twenty six cynomologous monkeys and six …
A generalized reference tissue model for quantification of dynamic PET with bolus plus continuous infusion tracer administration and pharmacological challenge
Methods A 4-parameter generalized reference tissue model (GRTM),(R1, k2, BP0, BP1) is
derived from a 3-parameter (R1, k2, BP) simplified reference tissue model (SRTM) by …
derived from a 3-parameter (R1, k2, BP) simplified reference tissue model (SRTM) by …
Advances in the quantification of [11C] raclopride dynamic PET with amphetamine challenges
The objective of the study is to improve the quantification of [11C] raclopride dynamic PET
with amphetamine challenges. Methods:[11C] raclopride was performed on two groups:(1) …
with amphetamine challenges. Methods:[11C] raclopride was performed on two groups:(1) …
A linear simplification of the parametric ntPET model for estimation of neurotransmitter response kinetics
M Normandin, R Badgaiyan, W Schiffer, E Morris - 2009 - Soc Nuclear Med
58 Objectives We previously demonstrated parametric ntPET (p-ntPET; Morris 2005, Morris
2008), a model for estimation of neurotransmitter (NT) kinetics from dynamic PET data. Here …
2008), a model for estimation of neurotransmitter (NT) kinetics from dynamic PET data. Here …
A combined PET-fMRI model for mapping neurotransmission: simulation and initial demonstration
97 Objectives The goal of this work is to develop a new kinetic model to simultaneously
analyze functional MRI (fMRI) and dynamic PET data with the objective of non-invasively …
analyze functional MRI (fMRI) and dynamic PET data with the objective of non-invasively …
Comparing IV amphetamine-induced 11C raclopride displacement between HRRT and GE advance PET: Implications for high resolution/sensitivity on dopmaine …
Background and aims: Psychostimulant-induced displacement of [11C] Raclopride (RAC),
often interpreted as a measure of intrasynaptic dopamine release, is increasingly used as a …
often interpreted as a measure of intrasynaptic dopamine release, is increasingly used as a …
Direct Parametric Reconstruction for Improved Characterization of Neurotransmitter Release using Dynamic PET
497 Objectives: Kinetic analyses of dynamic PET data with reversibly binding receptor-
ligand radiotracers can be used to detect endogenous neurotransmitter (NT) releases …
ligand radiotracers can be used to detect endogenous neurotransmitter (NT) releases …
A reference tissue forward model for improved PET accuracy using within-scan displacement studies
JB Mandeville, MA Levine… - Journal of Cerebral …, 2022 - journals.sagepub.com
We report a novel forward-model implementation of the full reference tissue model (fFTRM)
that addresses the fast-exchange approximation employed by the simplified reference tissue …
that addresses the fast-exchange approximation employed by the simplified reference tissue …