TERT promoter mutation predicts radioiodine-refractory character in distant metastatic differentiated thyroid cancer
X Yang, J Li, X Li, Z Liang, W Gao, J Liang… - Journal of nuclear …, 2017 - Soc Nuclear Med
Telomerase reverse transcriptase (TERT) promoter mutation has been reported to be
associated with aggressive characteristics in differentiated thyroid cancer (DTC). This study …
associated with aggressive characteristics in differentiated thyroid cancer (DTC). This study …
TERT promoter mutation in primary papillary thyroid carcinoma lesions predicts absent or lower 131i uptake in metastases
Z Meng, M Matsuse, V Saenko, S Yamashita… - IUBMB …, 2019 - Wiley Online Library
Genetic mutations play important roles in not only development of papillary thyroid
carcinoma (PTC) but also determination of its properties. The radioactive iodine refractory …
carcinoma (PTC) but also determination of its properties. The radioactive iodine refractory …
Prognostic effects of TERT promoter mutations are enhanced by coexistence with BRAF or RAS mutations and strengthen the risk prediction by the ATA or TNM …
YS Song, JA Lim, H Choi, JK Won, JH Moon, SW Cho… - Cancer, 2016 - Wiley Online Library
BACKGROUND Recent reports suggest that mutations in the promoter of the gene encoding
telomerase reverse transcriptase (TERT) affect thyroid cancer outcomes. METHODS In all …
telomerase reverse transcriptase (TERT) affect thyroid cancer outcomes. METHODS In all …
TERT promoter mutations are associated with distant metastases in papillary thyroid carcinoma
G Gandolfi, M Ragazzi, A Frasoldati… - European Journal of …, 2015 - academic.oup.com
Objective Transcriptional activating mutations in the promoter of the telomerase reverse
transcriptase (TERT) gene were reported at high frequency in aggressive poorly …
transcriptase (TERT) gene were reported at high frequency in aggressive poorly …
TERT mRNA Expression as a Novel Prognostic Marker in Papillary Thyroid Carcinomas
A Tanaka, M Matsuse, V Saenko, T Nakao… - Thyroid, 2019 - liebertpub.com
Background: Telomerase reverse transcriptase (TERT) promoter mutations have been found
in a subset of papillary thyroid carcinomas (PTCs) and are associated with tumor …
in a subset of papillary thyroid carcinomas (PTCs) and are associated with tumor …
TERT promoter mutations are a major indicator of poor outcome in differentiated thyroid carcinomas
M Melo, AG da Rocha, J Vinagre… - The Journal of …, 2014 - academic.oup.com
Context: Telomerase promoter mutations (TERT) were recently described in follicular cell-
derived thyroid carcinomas (FCDTC) and seem to be more prevalent in aggressive cancers …
derived thyroid carcinomas (FCDTC) and seem to be more prevalent in aggressive cancers …
Prognostic Significance of TERT Promoter Mutations in Papillary Thyroid Carcinomas in a BRAFV600E Mutation–Prevalent Population
Background: The role of telomerase reverse transcriptase (TERT) promoter mutations in
differentiated thyroid cancer has been well established. These mutations have a significantly …
differentiated thyroid cancer has been well established. These mutations have a significantly …
Telomerase in differentiated thyroid cancer: promoter mutations, expression and localization
M Muzza, C Colombo, S Rossi, D Tosi, V Cirello… - Molecular and cellular …, 2015 - Elsevier
Abstract Telomerase-reverse-transcriptase (TERT) promoter mutations have been recently
described in tumors. In the present large series, TERT mutations were found in 12% of …
described in tumors. In the present large series, TERT mutations were found in 12% of …
TERT Promoter Mutations and Their Association with BRAF V600E Mutation and Aggressive Clinicopathological Characteristics of Thyroid Cancer
Context: Promoter mutations chr5: 1,295,228 C> T and chr5: 1,295,250 C> T (termed C228T
and C250T, respectively) in the gene for telomerase reverse transcriptase (TERT) have …
and C250T, respectively) in the gene for telomerase reverse transcriptase (TERT) have …
[HTML][HTML] The role of TERT promoter mutations in postoperative and preoperative diagnosis and prognosis in thyroid cancer
A Jin, J Xu, Y Wang - Medicine, 2018 - journals.lww.com
Background: Telomerase reverse transcriptase (TERT) promoter mutations have been
described in different pathological types of thyroid cancers (TC). After many types of …
described in different pathological types of thyroid cancers (TC). After many types of …