1277 Objectives: his preliminary clinical study evaluated the safety, uptake kinetics and
diagnostic potential of a glutamine analog, 18 F-(2S, 4R) 4-fluoroglutamine (18 F-GLN), in …

Sustaining the growth of tumor cells requires extra energy and metabolic building blocks. In
addition to consuming glucose, glutamine may play the role as an alternative source of …

Purpose The purpose of this study was to compare dynamic 18 F-FGln PET/CT images of
healthy subjects and cancer patients and explore the best imaging phase for different …

18F-(2S, 4R)-4-fluoroglutamine (18F-FGln) is an investigational PET radiotracer for imaging
tumor glutamine flux and metabolism. The aim of this study was to investigate its …

57 Objectives: he aim of this study was to investigate the feasibility of using 18 F-(2S, 4R) 4-
fluoroglutamine (18 F-GLN) PET/CT imaging as a novel amino-acid based metabolism radio …

1363 Objectives-Methods Mice bearing human TNBC (HCC1806) or receptor positive breast
cancer (MCF-7) xenografts undergo [18 F] Fluoroglutamine PET imaging before and after …

Changes in gene expression, metabolism, and energy requirements are hallmarks of cancer
growth and self-sufficiency. Upregulation of the PI3K/Akt/mTor pathway in tumor cells has …

The PET radiotracer 18F-(2 S, 4 R) 4-fluoroglutamine (18F-Gln) reflects glutamine transport
and can be used to infer glutamine metabolism. Mouse xenograft studies have …

Purpose There is a need for an alternative PET probe, which does not show normal brain
tissue uptake in the evaluation of metastasis to the brain. Therefore, we investigate the …

Abstract The [18 F] Fluorocholine ([18 F] FCH) tracer for PET imaging has been proven to be
effective for several malignances. However, there are only a few studies related to its breast …