18F-labeled bombesin analogs for targeting GRP receptor-expressing prostate cancer
The gastrin-releasing peptide receptor (GRPR) is found to be overexpressed in a variety of
human tumors. The aim of this study was to develop 18F-labeled bombesin analogs for PET …
human tumors. The aim of this study was to develop 18F-labeled bombesin analogs for PET …
PET of tumors expressing gastrin-releasing peptide receptor with an 18F-labeled bombesin analog
I Dijkgraaf, GM Franssen, WJ McBride… - Journal of Nuclear …, 2012 - Soc Nuclear Med
The gastrin-releasing peptide receptor (GRPR) is overexpressed in human prostate cancer.
Bombesin (BBN) is a neurotransmitter of 14 amino acids and binds with selectivity and with …
Bombesin (BBN) is a neurotransmitter of 14 amino acids and binds with selectivity and with …
18F-labeled bombesin analog for specific and effective targeting of prostate tumors expressing gastrin-releasing peptide receptors
M Honer, L Mu, T Stellfeld, K Graham… - Journal of Nuclear …, 2011 - Soc Nuclear Med
Bombesin is a peptide exhibiting high affinity for the gastrin-releasing peptide receptor
(GRPr), which is highly overexpressed on prostate cancer cells. In the present study, we …
(GRPr), which is highly overexpressed on prostate cancer cells. In the present study, we …
microPET and autoradiographic imaging of GRP receptor expression with 64Cu-DOTA-[Lys3] bombesin in human prostate adenocarcinoma xenografts
X Chen, R Park, Y Hou, M Tohme… - Journal of Nuclear …, 2004 - Soc Nuclear Med
Overexpression of gastrin-releasing peptide (GRP) receptor (GRPR) in both androgen-
dependent (AD) and androgen-independent (AI) human neoplastic prostate tissues provides …
dependent (AD) and androgen-independent (AI) human neoplastic prostate tissues provides …
GRP receptor-targeted PET of a rat pancreas carcinoma xenograft in nude mice with a 68Ga-labeled bombesin (6–14) analog
J Schuhmacher, H Zhang, J Doll… - Journal of nuclear …, 2005 - Soc Nuclear Med
Bombesin (BN), a 14-amino-acid peptide, shows high affinity for the human gastrin-
releasing peptide receptor (GRP-r), which is overexpressed on several types of cancer …
releasing peptide receptor (GRP-r), which is overexpressed on several types of cancer …
Bombesin analogues for gastrin-releasing peptide receptor imaging
PK Nanda, U Pandey, BN Bottenus, TL Rold… - Nuclear medicine and …, 2012 - Elsevier
OBJECTIVES: The present study describes the design and development of a series of new
bombesin (BBN) antagonist peptide ligands of the form [64Cu-(NO2A-XD-Phe6-BBN (6-13) …
bombesin (BBN) antagonist peptide ligands of the form [64Cu-(NO2A-XD-Phe6-BBN (6-13) …
177Lu-AMBA: synthesis and characterization of a selective 177Lu-labeled GRP-R agonist for systemic radiotherapy of prostate cancer
LE Lantry, E Cappelletti, ME Maddalena… - Journal of Nuclear …, 2006 - Soc Nuclear Med
Gastrin-releasing peptide receptors (GRP-R) are upregulated in many cancers, including
prostate, breast, and lung. We describe a new radiolabeled bombesin (BBN) analog for …
prostate, breast, and lung. We describe a new radiolabeled bombesin (BBN) analog for …
In Vitro and in Vivo Characterization of Novel 18F-Labeled Bombesin Analogues for Targeting GRPR-Positive Tumors
L Mu, M Honer, J Becaud, M Martic… - Bioconjugate …, 2010 - ACS Publications
The gastrin-releasing peptide receptor (GRPR) is overexpressed on a number of human
tumors and has been targeted with radiolabeled bombesin analogues for the diagnosis and …
tumors and has been targeted with radiolabeled bombesin analogues for the diagnosis and …
Novel series of 111In-labeled bombesin analogs as potential radiopharmaceuticals for specific targeting of gastrin-releasing peptide receptors expressed on human …
Gastrin-releasing peptide (GRP) receptors have been shown to be expressed with high
densities on several types of cancer cells including prostate, breast, small cell lung, and …
densities on several types of cancer cells including prostate, breast, small cell lung, and …
Molecular Imaging of Gastrin-Releasing Peptide Receptor-Positive Tumors in Mice Using 64Cu- and 86Y-DOTA−(Pro1,Tyr4)-Bombesin(1−14)
GB Biddlecombe, BE Rogers, M De Visser… - Bioconjugate …, 2007 - ACS Publications
Bombesin is a tetradecapeptide neurohormone that binds to gastrin-releasing peptide
receptors (GRPR). GRPRs have been found in a variety of cancers including invasive breast …
receptors (GRPR). GRPRs have been found in a variety of cancers including invasive breast …