Identification of small nuclei in the brain by PET has been limited by the spatial resolution of
conventional scanners. The new detector technology and advanced signal analysis of a …

Rodent models and genetically altered mice have recently become available to study many
human diseases. A sensitive and accurate PET scanner for small animals would be useful to …

The purpose of this study was to evaluate the feasibility of absolute quantification of regional
cerebral glucose utilization (rCMRglc) in mice by use of 18F-FDG and a small animal PET …

The challenge of sampling blood from small animals has hampered the realization of
quantitative small-animal PET. Difficulties associated with the conventional blood-sampling …

Although 18F-FDG PET is an established technique to assess brain glucose use, a shorter
imaging time is preferable for patient convenience and increased throughput. The aim of this …

Purpose In this study, the contribution of the transaxial, coronal, and sagittal planes in
evaluations of regional cerebral glucose metabolism was investigated in healthy volunteers …

MATERIALS AND METhODS The procedure for the measurement of LCMRQ@ IUat our
institution involves the iv injection of 5— 10mCi of FDG as a 5-10 sec bolus with rapid …

The aim of this study was to evaluate various methods for estimating the metabolic rate of
glucose utilization in the mouse brain (cMRglc) using small-animal PET and reliable blood …

The anatomy of the thalamus and its connectivity with surrounding areas are known.
Localized metabolic activities at the thalamic substructural level have not been measured in …

In a previous publication the theory, procedure, and results of a method were described for
making two sequential measurements of cerebral metabolic rate for glucose (CMRglc) …