In a recent editorial Dr. Timothy Tewson (I) gave three possi bilities for the inconsistenciesin
the distribution of H-3 haloperidol and FI 8 haloperidol asdescribedby Zanzonico et al.(2) …

Reply Ingeneral, thevalidationivivoofaputativereceptor-binding radiotracer as such is
complicated by pharmacokinetic, metabolic, and pharmacological considerations. As …

There is a growing interest in the development of techniques for the external detection and
quantification of receptor sites in man. The first step in this procedure is the development of …

Haloperidol labeled with fluorine-18 (Ti/a= 110 min, positron emission 97%), prepared
yielding. 04 Ci/mlllimole by the Balz-Schiemann reaction, was evaluated in a murine model …

Neuroleptic receptor ligands, spiroperidol, benperidol and haloperidol were labeled with
fluorine-18 by a nucleophilic aromatic substitution reaction of p-nitrobenzo-nitrile with/sup …

No-Carrier-Added Biodistribution in Mice and Tomographic Studies in a Baboon Page 1
here is great interest in the application of positron labeled radioligands to map the …

.structures forlabelingwithâ€8F(JO).Theseproblems Page 1 Thedevelopment
ofpositronemissiontransaxialto mography (PETT) methods for studying neuro transmitter receptors …

PreparationandPreliminaryBiodistributionof â€â€NoCarrierAdded'â€Fluorine—18 Page 1
Following the development of positron emission to mography (1), several radiotnacers have …

MATERIALS AND METHODS Cesium carbonate was purchased commercially*.
Dimethylsulfoxide (DMSO) was a Gold Label rca gentt and was dried over 4 A molecular …

[en] Studies with the triazene method of radiofluorination are presented, including the
production and use of anhydrous H 18 F, investigations into the best reaction conditions …