Poly (vinylbenzyl-O-β-d-galactopyranosyl-d-gluconamide)(PVLA) can be specifically
internalized by hepatocytes via the asialoglycoprotein receptor. In this study, we synthesized …

Introduction Specific targeting of galactose-carrying molecule to ASGP-R in normal
hepatocytes has been demonstrated before. In this study, galactosyl polystyrene was …

This study investigated the usefulness of 99mTc hydrazinonicotinamide-galactosylated
chitosan (HGC) in hepatocyte imaging. HGC was obtained by coupling the galactose moiety …

The aim of this study is to develop a copolymer-based single-photon emission computed
tomography/magnetic resonance (SPECT/MR) dual-modality imaging agent that can be …

A novel bifunctional coupling agents-biomolecular compound DMP-NGA was prepared by
coupling the SATP with galactosyl-neoglycoalbumin (NGA). The DMP-NGA was labeled with …

Galactosyl-methylated chitosan (GMC) is a galactosylated chitosan (GC) that is chemically
modified to improve labeling efficiency with 99mTc compared with native GC. The aim of this …

99mTc-Labeled diethylenetriaminepentaacetic acid (DTPA)-coupled neogalactosyl human
serum albumin (GSA) is used as an imaging agent for asialoglycoprotein receptor of the …

Asialoglycoprotein receptor (ASGPR) specifically recognizes glycans terminated with β-d-
galactose or N-acetylgalactosamine. Its exclusive expression in mammalian hepatocytes …

Two galactose derivatives, a monovalent 99m Tc-MAMA-MGal galactoside and a divalent
99m Tc-MAMA-DGal galactoside, were synthesized and radiolabeled in high radiochemical …

Asialoglycoprotein receptors (ASGP-R) are well known to exist on the mammalian liver,
situate on the surface of hepatocyte membrane. Quantitative imaging of asialoglycoprotein …