99mTc-TRODAT-1 ([2-[[2-[[[3-(4-chlorophenyl)-8-methyl-8-azabicyclo [3, 2, 1] oct-2-yl]
methyl](2-mercaptoethyl) amino] ethyl] amino] ethanethiolato (3-)-N2, N2′, S2, S2′] oxo-[1 …

The imaging of dopamine transporter (DAT) with 99mTc-TRODAT-1 ([2-[[2-[[[3-(4-
chlorophenyl)-8-methyl-8-azabicyclo [3, 2, 1] oct-2-yl] methyl](2-mercaptoethyl) amino] ethyl] …

Functional brain imaging targeting the presynaptic dopamine nerve terminal of the
nigrostriatal system has been used for monitoring disease progression and evaluating …

Parkinson's disease (PD) is a degeneration of the nigrostriatal dopaminergic pathway,
leading to a selective loss of dopamine in the striatum. 99m Tc-TRODAT-1 is a recently …

Objective (s): 99m Tc-TRODAT-1, which binds to the dopamine transporter, could be used to
image the dopaminergic system in diagnosis of Parkinson's disease (PD). PD can be …

Nigral dopaminergic projections to the striatum are targeted in Parkinson's disease (PD).
The extent of the degeneration of the dopaminergic system in PD can be visualised by …

Purpose The aim of this study was to assess the utility of presynaptic dopaminergic imaging
using 99m Tc-TRODAT-1 SPECT/CT and 18 F-FDOPA PET/CT and compare their …

Background Although the decrease in striatal dopamine transporter (DAT) density has been
described in North American, European, and Asian Parkinson's disease (PD) patients …

Parkinson's disease is a progressive neurodegenerative disorder characterized by a
selective loss of dopamine in the striatum. Problems remain in the accurate diagnosis of …

Abstract 99m Tc-TRODAT-1 is the first clinical routine 99m Tc radiopharmaceutical to
evaluate dopamine neurons loss in Parkinson's disease (PD). 18 F-AV-133 is a novel PET …