Imaging proliferation in brain tumors with 18F-FLT PET: comparison with 18F-FDG

W Chen, T Cloughesy, N Kamdar… - Journal of Nuclear …, 2005 - Soc Nuclear Med
3′-Deoxy-3′-18F-fluorothymidine (18F-FLT) is a recently developed PET tracer to image
tumor cell proliferation. We characterized 18F-FLT PET of brain gliomas and compared 18F …

[18F]3′-deoxy-3′-fluorothymidine PET for the diagnosis and grading of brain tumors

SJ Choi, JS Kim, JH Kim, SJ Oh, JG Lee, CJ Kim… - European journal of …, 2005 - Springer
Abstract The aim of this study was to evaluate the feasibility of using [18 F] 3′-deoxy-3′-
fluorothymidine (FLT) positron emission tomography (PET) for the diagnosis and grading of …

Comparison of 18F-FET and 18F-FDG PET in brain tumors

D Pauleit, G Stoffels, A Bachofner, FW Floeth… - Nuclear medicine and …, 2009 - Elsevier
The purpose of this study was to compare the diagnostic value of positron emission
tomography (PET) using [18F]-fluorodeoxyglucose (18F-FDG) and O-(2-[18F] fluoroethyl)-l …

18F-fluorothymidine kinetics of malignant brain tumors

C Schiepers, W Chen, M Dahlbom, T Cloughesy… - European journal of …, 2007 - Springer
Purpose 18 F-labeled deoxy-fluorothymidine (FLT), a marker of cellular proliferation, has
been used in PET tumor imaging. Here, the FLT kinetics of malignant brain tumors were …

[18F]FLT-PET in oncology: current status and opportunities

LB Been, AJH Suurmeijer, DCP Cobben… - European journal of …, 2004 - Springer
Abstract In recent years,[18 F]-fluoro-3′-deoxy-3′-L-fluorothymidine ([18 F] FLT) has been
developed as a proliferation tracer. Imaging and measurement of proliferation with PET …

3′-[18F]Fluoro-3′-Deoxythymidine ([18F]-FLT) as Positron Emission Tomography Tracer for Imaging Proliferation in a Murine B-Cell Lymphoma Model and in the …

M Wagner, U Seitz, A Buck, B Neumaier, S Schultheiß… - Cancer research, 2003 - AACR
Here we describe the evaluation of 3′-[18F] fluoro-3′-deoxythymidine {[18F]-FLT} as a
tracer for positron emission tomography (PET) in a murine model of B-cell lymphoma and in …

Imaging proliferation in lung tumors with PET: 18F-FLT versus 18F-FDG

AK Buck, G Halter, H Schirrmeister… - Journal of nuclear …, 2003 - Soc Nuclear Med
Recently, the thymidine analog 3′-deoxy-3′-18F-fluorothymidine (FLT) was suggested for
imaging tumoral proliferation. In this prospective study, we examined whether 18F-FLT …

Correlation of 6-18F-fluoro-L-dopa PET uptake with proliferation and tumor grade in newly diagnosed and recurrent gliomas

BJ Fueger, J Czernin, T Cloughesy… - Journal of Nuclear …, 2010 - Soc Nuclear Med
6-18F-fluoro-l-dopa (18F-FDOPA) measured with PET as a biomarker of amino acid uptake
has been investigated in brain tumor imaging. The aims of the current study were to …

18F-FDOPA PET imaging of brain tumors: comparison study with 18F-FDG PET and evaluation of diagnostic accuracy

W Chen, DHS Silverman, S Delaloye… - Journal of Nuclear …, 2006 - Soc Nuclear Med
We evaluated the amino acid and glucose metabolism of brain tumors by using PET with 3,
4-dihydroxy-6-18F-fluoro-l-phenylalanine (18F-FDOPA) and 18F-FDG. Methods: Eighty-one …

Diagnostic performance of 18F-FET PET in newly diagnosed cerebral lesions suggestive of glioma

M Rapp, A Heinzel, N Galldiks, G Stoffels… - Journal of nuclear …, 2013 - Soc Nuclear Med
The aim of this study was to assess the clinical value of O-(2-18F-fluoroethyl)-l-tyrosine (18F-
FET) PET in the initial diagnosis of cerebral lesions suggestive of glioma. Methods: In a …