Drug-targeting strategies can increase the efficacy and reduce the side effects and toxicity of
conventional chemotherapy or may lead to new radiolabeled molecules useful for diagnosis …

Purpose: Selective delivery of drugs into the target tissue is expected to result in high drug
concentrations in the tissue of interest and therefore enhanced drug efficacy. To develop a …

Peptides are useful tools for the targeted delivery of radionuclides or chemotherapeutic
drugs to their site of action within an organism. Given that the peptide receptor is …

The transfer of peptide sequences identified by screening of phage-displayed libraries to
clinical application is often difficult. This study investigated whether coupling of a new …

The specific binding of peptides to their receptors can be used to meet the key requirement
in tumor targeting: selective addressing of neoplasm. Because of their small size, peptides …

Recent years have seen an increased effort in the development of peptide based
radiopharmaceuticals for nuclear medicine applications in imaging and therapy. This field is …

Purpose: The therapeutic effect of directly labeled antibodies in solid tumors is limited,
mainly due to the relatively low uptake of the radiolabeled antibody in tumors as compared …

Over the last decade, there has been a significant and rapidly growing interest in the use of
radiolabeled receptor-binding peptides for both nuclear imaging and targeted radiotherapy …

INTRODUCTION: Phosphopeptides represent interesting compounds to study and elucidate
cellular protein phosphorylation/dephosphorylation processes underlying various signal …

Two neuropeptides, bombesin (BBS) and neurotensin (NT) and their radiolabeled
analogues, have great potential for tumour targeting, either for diagnosis (eg, with 99mTc) or …