The present study estimated radiation-absorbed doses of the dopamine D1 receptor
radioligand [11C]((+)-8-chloro-5-(7-benzofuranyl)-7-hydroxy-3-methyl-2, 3, 4, 5-tetrahydro-1 …

NNC 22-0010 is a new dopamine antagonist with a high affinity and selectivity for D1
receptors in vitro. NNC 22-0010 has both an N-methyl group and a bromine, which allows …

Whole-body radiation dosimetry of 11C-raclopride was performed in healthy human
volunteers. Methods: Subjects (n= 6) were scanned with PET. Subjects received single …

NNC 22-0215 has been found to be a metabolically stable dopamine D1 antagonist with
high affinity and selectivity for D1 receptors in vitro. We prepared [11C] NNC 22-0215 with a …

Abstract Purpose [11 C] FLB 457, a radioligand with very high affinity and selectivity for
dopamine D 2/3 receptors, is used to measure receptor binding in extrastriatal regions …

PET has been used to examine changes in neurotransmitter concentrations in the living
brain. Pioneering PET studies on the dopamine system have used D2 and D3 receptor …

The research discussed in this article aimed to characterize better the biodistribution,
excretion and radiation dosimetry of the single photon emission computed tomography …

We measured the whole-body distribution of intravenously injected 11C-N-
propylnorapomorphine (11C-NPA), a dopamine agonist PET tracer, in human subjects and …

MATERIALS AND METhODS Radiopharmaceutical Iodine-125 SCH 23982 (R-(+)-8-['251]
iodo-7-hydroxy 2, 3, 4, 5-tetrahydro-3-methyl-5-phenyl-lH-3-benzazepine) in 50% n …

(+)-[76Br] A-69024 is a specific and enantioselective dopamine D1 receptor radioligand. The
Bmax of (+)-[76Br] A-69024 measured in vitro on rat striatum membranes was 320±25 …