Tissue distribution of 14C-diphenylhydantoin (14C-DPH) in the toadfish, with particular
reference to the pancreatic islet cells, was studied in 24 toadfish at intervals of 10 min to 72 …

Carbon-14-diphenylhydantoin(DPH) concen trated maximally in pancreatic islet cells of the
toad/ish 10 mm after its intravenous adminis tration. The islet cell-to-acinar-tissue ratio at this …

Our previous studies have shown a high accumulation of [125 I] N, N, N′-trimethyl-N′-(2-
hydroxy-3-methyl-5-iodobenzyl)-l, 3-propanediamine (HIPDM) in the human pancreas. In …

Curie quantities (0.3--1.5 Ci) of H11CN were used in the synthesis of C-11-tagged phenytoin
(C-11. DPH) and 5-(p-hydroxyphenyl)-5-phenylhydantoin (C-11. HPPH), using a modified …

RESULTS IodIne-I25. 1@ ctreotIde Figure 2 shows typical time courses of total radioactiv ity,
peptide-bound radioactivity and liberated 1@ Iin the medium and bile after …

Synthesis, characteristics and radioiodination of the new carboxylic derivatives of dithizone
are described in this paper. We have applied the carboxy dithizones for preparation of …

Three radioiodinated phenytoin analogs were synthesized, and tissue distribution studies
were conducted in rats. Except for a greater retention of radioactivity following administration …

Metabolic half-life of L-[U-14 C] histidine was detemined on the blood and white muscle of
rainbow trout Salmo gairdneri, Incorporation of the label into histidine related dipeptides …

We describe a radioimmunoassay procedure for the measurement of phenytoin (5, 5-
diphenylhydantoin) in serum samples. Antiserum to phenytoin has been produced against …

RESULTS Expedment A Significant specific tissue binding of †œIn-pentetreotide was
observed in the octreotide receptor-positive anterior pituitary gland, adrenals, and pancreas …