Cardiac Beta-Adrenergic Receptor Downregulation, Evaluated by Cardiac Positron Emission Tomography, in Chronotropic Incompetence
T Goto, S Kikuchi, K Mori, T Nakayama… - Journal of Nuclear …, 2020 - Soc Nuclear Med
The mechanism of chronotropic incompetence (CI), which has been associated with
autonomic dysfunction, has not been elucidated in patients without heart failure (HF) …
autonomic dysfunction, has not been elucidated in patients without heart failure (HF) …
Cardiac β-adrenergic receptor downregulation, evaluated by cardiac PET, in chronotropic incompetence
T Goto, S Kikuchi, K Mori, T Nakayama… - Journal of Nuclear …, 2021 - Soc Nuclear Med
The mechanism of chronotropic incompetence (CTI), which has been associated with
autonomic dysfunction, has not been elucidated in patients without heart failure (HF) …
autonomic dysfunction, has not been elucidated in patients without heart failure (HF) …
impact of cardiac beta-adrenergic receptor density evaluated by cardiac PET on chronotropic incompetence
T Goto, S Kikuchi, K Mori, K Nakasuka, M Kato… - Circulation, 2017 - Am Heart Assoc
Introduction: Chronotropic incompetence (CI), defined as the inability of the heart to increase
its rate commensurate with increased activity, produces exercise intolerance, and is an …
its rate commensurate with increased activity, produces exercise intolerance, and is an …
Mechanisms of chronotropic incompetence in heart failure with preserved ejection fraction
Background: Chronotropic incompetence is common in heart failure with preserved ejection
fraction (HFpEF) and is associated with impaired aerobic capacity. We investigated the …
fraction (HFpEF) and is associated with impaired aerobic capacity. We investigated the …
Chronotropic incompetence in chronic heart failure
AL Clark, AJS Coats - International journal of cardiology, 1995 - Elsevier
Background: The exercise limitation of patients with chronic heart failure may be due in part
to an inability to increase heart rate as normal, a limitation sometimes referred to as …
to an inability to increase heart rate as normal, a limitation sometimes referred to as …
Decreased myocardial β-adrenergic receptor density in relation to increased sympathetic tone in patients with nonischemic cardiomyopathy
T Tsukamoto, K Morita, M Naya… - Journal of Nuclear …, 2007 - Soc Nuclear Med
Cardiac sympathetic function plays an important role in the regulation of left ventricular (LV)
function and the pathophysiology of LV dysfunction. 11C-CGP-12177 (11C-CGP) has been …
function and the pathophysiology of LV dysfunction. 11C-CGP-12177 (11C-CGP) has been …
Characterization and prognostic importance of chronotropic incompetence in heart failure with preserved ejection fraction
N Yuasa, M Obokata, T Harada, K Kagami… - Journal of …, 2024 - Elsevier
Background Exercise intolerance is the primary symptom of patients with heart failure with
preserved ejection fraction (HFpEF). Chronotropic incompetence has been considered to be …
preserved ejection fraction (HFpEF). Chronotropic incompetence has been considered to be …
Chronotropic incompetence, beta‐blockers, and functional capacity in advanced congestive heart failure: time to pace?
UP Jorde, TJ Vittorio, ME Kasper… - European journal of …, 2008 - Wiley Online Library
Background: Chronotropic incompetence (CI) is often seen in subjects with chronic
congestive heart failure (CHF). The prevalence of CI, its mechanisms and association with …
congestive heart failure (CHF). The prevalence of CI, its mechanisms and association with …
Association of chronic kidney disease with chronotropic incompetence in heart failure with preserved ejection fraction
DA Klein, DH Katz, L Beussink-Nelson… - The American journal of …, 2015 - Elsevier
Chronotropic incompetence (CI) is common in heart failure with preserved ejection fraction
(HFpEF) and may be a key reason underlying exercise intolerance in these patients …
(HFpEF) and may be a key reason underlying exercise intolerance in these patients …
Chronotropic incompetence: An obscure cause of heart failure symptoms in survivors of critical diseases?
K Yalta, T Yalta, N Sıvrı, Y Aksoy… - International …, 2011 - internationaljournalofcardiology.com
In their recently published article, Ruiz-Bailén M et al. prospectively investigated the course
of myocardial dysfunction that had developed in a group of critically ill patients, and …
of myocardial dysfunction that had developed in a group of critically ill patients, and …
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