CardioPET, a potential PET tracer for coronary artery disease, exhibits higher heart-to-liver ratios in fed mice and rats
T Shoup, D Elmaleh, E Carter, D Winter, C Tolman… - 2009 - Soc Nuclear Med
1933 Objectives CardioPET (trans-9-[18 F] fluoro-3, 4-methyleneheptadecanoic acid), a
modified fatty acid closely resembling naturally-occurring free fatty acids, undergoes …
modified fatty acid closely resembling naturally-occurring free fatty acids, undergoes …
Comparison of uptake of CardioPET, a potential PET tracer for myocardial fatty acid utilization and BFPET, a possible PET blood flow marker in fed vs fasted mice
E Carter, D Elmaleh, T Shoup, A Bonab, K Paul… - 2011 - Soc Nuclear Med
1098 Objectives CardioPET (trans-9-[18F] fluoro-3, 4-methyleneheptadecanoic acid), a
modified fatty acid closely resembling naturally-occurring free fatty acids, undergoes …
modified fatty acid closely resembling naturally-occurring free fatty acids, undergoes …
A phase I study evaluating myocardial pharmacokinetic behavior of CardioPET, a new cardiac PET tracer, in normal subjects and subjects with stable coronary artery …
A Kardan, T Shoup, S Barrow, S Dragotakes… - 2008 - Soc Nuclear Med
834 Objectives: CardioPET (trans-9-[18 F] fluoro-3, 4-methyleneheptadecanoic acid), a
modified fatty acid closely resembling naturally occurring fatty acids, undergoes metabolic …
modified fatty acid closely resembling naturally occurring fatty acids, undergoes metabolic …
Biodistribution of CardioPET as a PET tracer for estimating and differentiating fat deposit function in mice
E Carter, T Shoup, D Winter, C Tolman, D Elmaleh… - 2008 - Soc Nuclear Med
1292 Objectives: To evaluate the uptake behavior of CardioPET in brown and white fat in
rats and in fed and fasted mice. In contrast to other species, adult mice keep brown fat …
rats and in fed and fasted mice. In contrast to other species, adult mice keep brown fat …
A phase I study to evaluate the safety and biodistribution of CardioPET as a new cardiac PET tracer: Studies in normal subjects
A Kardan, T Shoup, S Barrow, S Dragotakes… - 2008 - Soc Nuclear Med
278 Objectives: CardioPET (trans-9-[18 F] fluoro-3, 4-methyleneheptadecanoic acid) is a
modified fatty acid closely resembling naturally occurring fatty acids (FFAs). FFAs are the …
modified fatty acid closely resembling naturally occurring fatty acids (FFAs). FFAs are the …
Synthesis and preliminary evaluation of an 18F-labeled oleic acid analog for PET imaging of fatty acid uptake and metabolism
Introduction Imaging fatty acid uptake and utilization has broad impact in investigating
myocardial diseases, hepatic functions, tumor progression, and the metabolic state of …
myocardial diseases, hepatic functions, tumor progression, and the metabolic state of …
Modified Synthesis and Assessment of 18F-FTP for Cardiac Ischemia/Reperfusion Injury in Rats
T Gu - 2020 - Soc Nuclear Med
1386 Introduction: PET fatty acid tracers have the ability to reflect myocardial β-oxidation.
Specifically, ischemic myocardium metabolizes glucose preferentially, with reduced MFAO …
Specifically, ischemic myocardium metabolizes glucose preferentially, with reduced MFAO …
Evaluation of trans-9-18F-fluoro-3, 4-Methyleneheptadecanoic acid as a PET tracer for myocardial fatty acid imaging
TM Shoup, DR Elmaleh, AA Bonab… - Journal of Nuclear …, 2005 - Soc Nuclear Med
This study describes the radiosynthesis and preliminary biologic evaluation of trans-9 (RS)-
18F-fluoro-3, 4 (RS, RS)-methyleneheptadecanoic acid (18F-FCPHA) as a new potential …
18F-fluoro-3, 4 (RS, RS)-methyleneheptadecanoic acid (18F-FCPHA) as a new potential …
Synthesis and preliminary evaluation of 18F-labeled 4-thia palmitate as a PET tracer of myocardial fatty acid oxidation
TR DeGrado, S Wang, JE Holden, RJ Nickles… - Nuclear medicine and …, 2000 - Elsevier
Interest remains strong for the development of a noninvasive technique for assessment of
regional fatty acid oxidation rate in the myocardium. 18F-labeled 4-thia palmitate (FTP, 16 …
regional fatty acid oxidation rate in the myocardium. 18F-labeled 4-thia palmitate (FTP, 16 …
Synthesis and preliminary evaluation of 18-[18F] fluoro-4-thia-oleic acid (FTO) as a PET probe of fatty acid oxidation
M Pandey, F Bhattacharyya, A Belanger, S Wang… - 2010 - Soc Nuclear Med
585 Objectives Fatty acid oxidation (FAO) is a major energy providing process with important
implications in cardiovascular, oncologic, neurologic and metabolic diseases. A novel 4-thia …
implications in cardiovascular, oncologic, neurologic and metabolic diseases. A novel 4-thia …