[PDF][PDF] Variables influencing tumor dosimetry in radioimmunotherapy of CEA-expressing cancers with anti-CEA and antimucin monoclonal antibodies
TM Behr, RM Sharkey, ME Juweid… - Journal of Nuclear …, 1997 - Soc Nuclear Med
Variables Influencing Tumor Dosimetry in Radioimmunotherapy of CEA-Expressing Cancers
with Anti-CEA and Antimucin Monoclonal Ant Page 1 6. Lamb DJ, Bullock DW, Hoyte RM, et al …
with Anti-CEA and Antimucin Monoclonal Ant Page 1 6. Lamb DJ, Bullock DW, Hoyte RM, et al …
Factors influencing the pharmacokinetics, dosimetry, and diagnostic accuracy of radioimmunodetection and radioimmunotherapy of carcinoembryonic antigen …
The aim of this study was to examine factors that may influence the pharmacokinetics,
diagnostic accuracy, and dosimetry in radioimmunodetection and radioimmunotherapy with …
diagnostic accuracy, and dosimetry in radioimmunodetection and radioimmunotherapy with …
Factors influencing hematologic toxicity of radioimmunotherapy with 131I‐labeled anti‐carcinoembryonic antigen antibodies
BACKGROUND Several investigators have reported a considerable variability in the
observed hematologic toxicity after radioimmunotherapy (RAIT) with monoclonal antibodies …
observed hematologic toxicity after radioimmunotherapy (RAIT) with monoclonal antibodies …
The effect of second antibody clearance on the distribution and dosimetry of radiolabelled anti‐cea antibody in a human colonic tumor xenograft model
RB Pedley, R Dale, JA Boden… - … journal of cancer, 1989 - Wiley Online Library
Radioimmunotherapy in humans is limited by toxicity to normal tissues, caused by
circulating radio‐antibody. Second antibody directed against the first (anti‐tumor) antibody …
circulating radio‐antibody. Second antibody directed against the first (anti‐tumor) antibody …
Lack of radioimmunodetection and complications associated with monoclonal anticarcinoembryonic antigen antibody cross-reactivity with an antigen on circulating …
RO Dillman, JC Beauregard, RE Sobol, I Royston… - Cancer research, 1984 - AACR
Abstract Characterization of several high-affinity murine monoclonal anticarcinoembryonic
antigen (CEA) antibodies suggested good specificity except for cross-reactivity with an …
antigen (CEA) antibodies suggested good specificity except for cross-reactivity with an …
[PDF][PDF] Prediction of hematologic toxicity after radioimmunotherapy with 131I-labeled anticarcinoembryonic antigen monoclonal antibodies
This studywas undertakento determinethe factorsaffecting myelotoxicityafter
radioimmunotherapy (RAIT) with 1311-labeled anticarcinoembryonicantigen (anti-CEA) …
radioimmunotherapy (RAIT) with 1311-labeled anticarcinoembryonicantigen (anti-CEA) …
A Phase I Radioimmunotherapy Trial Evaluating 90Yttrium-labeled Anti-Carcinoembryonic Antigen (CEA) Chimeric T84.66 in Patients with Metastatic CEA-producing …
JYC Wong, DZ Chu, DM Yamauchi, LE Williams… - Clinical cancer …, 2000 - AACR
Abstract Chimeric T84. 66 (cT84. 66) is a genetically engineered human/murine chimeric
IgG1 with high affinity and specificity to carcinoembryonic antigen (CEA). The purpose of this …
IgG1 with high affinity and specificity to carcinoembryonic antigen (CEA). The purpose of this …
Relationship between tumour size and uptake of radiolabelled anti-CEA in a colon tumour xenograft
RB Pedley, J Boden, PA Keep, PJ Harwood… - European journal of …, 1987 - Springer
The relationship between tumour size and the uptake of three radiolabelled anti-CEA
localising antibodies (A5B7, 1H12 and PK2G) into a human colon tumour xenograft (MaWi) …
localising antibodies (A5B7, 1H12 and PK2G) into a human colon tumour xenograft (MaWi) …
The effect of tumor CEA content and tumor size on tissue uptake of indium 111‐labeled anti‐CEA monoclonal antibody
VJ Philben, JG Jakowatz, BG Beatty, WG Vlahos… - Cancer, 1986 - Wiley Online Library
This study was undertaken to determine the effect of tumor size and tumor carcinoembryonic
antigen (CEA) content on the uptake of indium 111 (111In)‐labeled anti‐CEA monoclonal …
antigen (CEA) content on the uptake of indium 111 (111In)‐labeled anti‐CEA monoclonal …
Radioimmunotherapy of human colon carcinoma by 131I‐labelled monoclonal anti‐cea antibodies in a nude mouse model
F Buchegger, A Vacca, S Carrel… - … journal of cancer, 1988 - Wiley Online Library
A mixture of 3 MAbs directed against 3 different CEA epitopes was radiolabelled with 131I
and used for the treatment of a human colon carcinoma transplanted sc into nude mice …
and used for the treatment of a human colon carcinoma transplanted sc into nude mice …