Fibroblast activation protein (FAP), which promotes tumor growth and progression, is
overexpressed in cancer-associated fibroblasts of many human epithelial cancers. Because …

Purpose Fibroblast activation protein (FAP), which has high expression in cancer-associated
fibroblasts of epithelial cancers, can be used as a theranostic target. Our previous study …

Purpose Fibroblast activation protein (FAP) is a membrane-bound protease that has limited
expression in normal adult tissues but is highly expressed in the tumor microenvironment of …

Fibroblast activation protein (FAP) has emerged as an interesting molecular target used in
the imaging and therapy of various types of cancers. 68Ga-labeled chelator-linked FAP …

Cancer-associated fibroblasts constitute a vital subpopulation of the tumor stroma and are
present in more than 90% of epithelial carcinomas. The overexpression of the serine …

Fibroblast activation protein (FAP) is overexpressed in cancer-associated fibroblasts and is
involved in a variety of tumor-promoting activities such as matrix remodeling, angiogenesis …

Fibroblast activation protein (FAP)–expressing cancer-associated fibroblasts confer
treatment resistance and promote metastasis and immunosuppression. Because FAP is …

Cancer-associated fibroblasts (CAFs) are crucial components of the tumor
microenvironment. Fibroblast activation protein (FAP) is overexpressed in CAFs. FAP …

Targeting cancer-associated fibroblasts (CAFs) has become an attractive goal for diagnostic
imaging and therapy because they can constitute as much as 90% of a tumor mass. The …

Several radiopharmaceuticals targeting fibroblast activation protein (FAP) based on the
highly potent FAP inhibitor UAMC1110 are currently under investigation. Pre-clinical as well …