The goal of this paper was to evaluate the in vivo kinetics of the novel tau-specific PET
radioligand 18F-AV-1451 in cognitively healthy control (HC) and Alzheimer disease (AD) …

This study compared the in vivo imaging characteristics of tau PET ligands 18F-THK-5351
and 18F-THK-5317 in the context of Alzheimer disease (AD). Additionally, reference tissue …

18F-T807 is a PET radiotracer developed for imaging tau protein aggregates, which are
implicated in neurologic disorders including Alzheimer disease and traumatic brain injury …

18F-AV-1451 is currently the most widely used of several experimental tau PET tracers. The
objective of this study was to evaluate 18F-AV-1451 binding with full kinetic analysis using a …

We report kinetic modeling results of dynamic acquisition data from 0 to 100 min after
injection with the tau PET tracer 18F-AV-1451 in 19 subjects. Methods: Subjects were …

Tau PET imaging has potential for elucidating changes in the deposition of
neuropathological tau aggregates that are occurring during the progression of Alzheimer …

Purpose The tau tracer [18 F] AV1451, also known as flortaucipir, is a promising ligand for
imaging tau accumulation in Alzheimer's disease (AD). Most of the previous studies have …

Because a correlation between tau pathology and the clinical symptoms of Alzheimer
disease (AD) has been hypothesized, there is increasing interest in developing PET tracers …

In this study, we have synthesized and evaluated 18F-JNJ64349311, a tracer with high
affinity for aggregated tau (inhibition constant value, 8 nM) and high (≥ 500×) in vitro …

18F-PI-2620 is a PET tracer with high binding affinity for aggregated tau, a key pathologic
feature of Alzheimer disease (AD) and other neurodegenerative disorders. Preclinically, 18F …