Several groups have developed high-resolution PET systems and shown the feasibility of in
vivo studies on small laboratory animals. In this investigation, one of these systems was …

Substituted benzamides such as 11C-raclopride or 123I-iodobenzamide are selective
radiotracers for PET and SPECT imaging of D2-like dopamine (DA) receptors. 18F …

There is considerable interest in using positron emission tomography (PET) imaging to
understand the function of dopamine D3 receptors. Due to high sequence homology with D2 …

Dopaminergic neurotransmission in extrastriatal regions may play a crucial role in the
pathophysiology and treatment of neuropsychiatric disorders. The high-affinity radioligands …

The increasing use of genetically engineered mice as animal models of human disease in
biomedical research, latest advances in imaging technologies, and development of novel …

A recent investigation showed that intracerebral radioactivity concentrations can reliably be
quantified in vivo with a small-animal PET device. The purpose of the current study was to …

[18F] Fallypride PET studies can be used to estimate the nondisplaceable binding potential
(BPND) in vivo of dopamine D2/D3 receptor-rich regions of the brain. These studies often …

PET has been used to examine changes in neurotransmitter concentrations in the living
brain. Pioneering PET studies on the dopamine system have used D2 and D3 receptor …

The neurotransmitter dopamine plays a role in many different functions of the human brain,
ranging from psychomotor planning to cognition. This short review addresses which parts of …

The novel, dedicated small animal PET tomograph, quad-HIDAC, offers submillimeter
resolution in instrumental characterization experiments. The aim of this study was to …