18F-DCFBC PET/CT for PSMA-based detection and characterization of primary prostate cancer

SP Rowe, KL Gage, SF Faraj, KJ Macura… - Journal of Nuclear …, 2015 - Soc Nuclear Med
We previously demonstrated the ability to detect metastatic prostate cancer using N-[N-[(S)-
1, 3-dicarboxypropyl] carbamoyl]-4-18F-fluorobenzyl-l-cysteine (18F-DCFBC), a low …

Comparison of prostate-specific membrane antigen–based 18F-DCFBC PET/CT to conventional imaging modalities for detection of hormone-naïve and castration …

SP Rowe, KJ Macura, A Ciarallo, E Mena… - Journal of Nuclear …, 2016 - Soc Nuclear Med
Conventional imaging modalities (CIMs) have limited sensitivity and specificity for detection
of metastatic prostate cancer. We examined the potential of a first-in-class radiofluorinated …

A prospective comparison of 18F-sodium fluoride PET/CT and PSMA-targeted 18F-DCFBC PET/CT in metastatic prostate cancer

SA Harmon, E Bergvall, E Mena, JH Shih… - Journal of Nuclear …, 2018 - Soc Nuclear Med
The purpose of this study was to compare the diagnostic performance of 18F-DCFBC
PET/CT, a first-generation 18F-labeled prostate-specific membrane antigen (PSMA) …

PSMA-Based [18F]DCFPyL PET/CT Is Superior to Conventional Imaging for Lesion Detection in Patients with Metastatic Prostate Cancer

SP Rowe, KJ Macura, E Mena, AL Blackford… - Molecular imaging and …, 2016 - Springer
Purpose Current standard of care conventional imaging modalities (CIM) such as X-ray
computed tomography (CT) and bone scan can be limited for detection of metastatic prostate …

PSA-stratified performance of 18F-and 68Ga-PSMA PET in patients with biochemical recurrence of prostate cancer

F Dietlein, C Kobe, S Neubauer… - Journal of Nuclear …, 2017 - Soc Nuclear Med
Several studies outlined the sensitivity of 68Ga-labeled PET tracers against the prostate-
specific membrane antigen (PSMA) for localization of relapsed prostate cancer in patients …

18F-DCFPyL PET/CT in the detection of prostate cancer at 60 and 120 minutes: detection rate, image quality, activity kinetics, and biodistribution

M Wondergem, FM van der Zant, RJJ Knol… - Journal of Nuclear …, 2017 - Soc Nuclear Med
There is increasing interest in PET/CT with prostate-specific membrane antigen (PSMA)
tracers for imaging of prostate cancer because of the higher detection rates of prostate …

68Ga-PSMA-11 dynamic PET/CT imaging in primary prostate cancer

C Sachpekidis, K Kopka, M Eder… - Clinical nuclear …, 2016 - journals.lww.com
Purpose The aim of our study is to assess the pharmacokinetics and biodistribution of 68 Ga-
PSMA-11 in patients suffering from primary prostate cancer (PC) by means of dynamic and …

Matched-pair comparison of 18F-DCFPyL PET/CT and 18F-PSMA-1007 PET/CT in 240 prostate cancer patients: interreader agreement and lesion detection rate of …

M Wondergem, FM van der Zant… - Journal of Nuclear …, 2021 - Soc Nuclear Med
Over 20 different prostate-specific membrane antigen (PSMA)–targeting
radiopharmaceuticals for both imaging and therapy have been synthesized. Although …

68Ga-PSMA-11 PET/CT in newly diagnosed carcinoma of the prostate: correlation of intraprostatic PSMA uptake with several clinical parameters

SA Koerber, MT Utzinger, C Kratochwil… - Journal of Nuclear …, 2017 - Soc Nuclear Med
68Ga-prostate-specific membrane antigen (PSMA) PET/CT is a promising diagnostic tool for
patients with prostate cancer. Our study evaluates SUVs in benign prostate tissue and …

[HTML][HTML] Early lesion detection with 18F-DCFPyL PET/CT in 248 patients with biochemically recurrent prostate cancer

M Wondergem, BHE Jansen, FM van der Zant… - European journal of …, 2019 - Springer
Purpose Prostate-specific membrane antigen (PSMA) PET/CT is increasingly used in
patients with biochemically recurrent prostate cancer (BCR), mostly using gallium-68 (168 …