Whole-body imaging of high-dose ionizing irradiation-induced tissue injuries using 99mTc-duramycin

SE Johnson, Z Li, Y Liu, JE Moulder… - Journal of Nuclear …, 2013 - Soc Nuclear Med
High-dose ionizing irradiation can cause extensive injuries in susceptible tissues. A
noninvasive imaging technique that detects a surrogate marker of apoptosis may help …

Noninvasive whole-body imaging of phosphatidylethanolamine as a cell death marker using 99mTc-duramycin during TNF-induced SIRS

T Delvaeye, S Deleye, K Lemeire… - Journal of Nuclear …, 2018 - Soc Nuclear Med
Systemic inflammatory response syndrome (SIRS) is an inflammatory state affecting the
whole body. It is associated with the presence of pro-and antiinflammatory cytokines in …

Imaging radiation-induced normal tissue injury to quantify regional dose response

DV Fried, SK Das, LB Marks - Seminars in Radiation Oncology, 2017 - Elsevier
Noninvasive imaging has and will continue to play a pivotal role in the assessment of
radiation-induced normal tissue toxicity. In this review, we will examine key literature …

Imaging radiation-induced normal tissue injury

ME Robbins, JK Brunso-Bechtold… - Radiation …, 2012 - meridian.allenpress.com
Technological developments in radiation therapy and other cancer therapies have led to a
progressive increase in five-year survival rates over the last few decades. Although acute …

Imaging for assessment of radiation-induced normal tissue effects

R Jeraj, Y Cao, RK Ten Haken, C Hahn… - International Journal of …, 2010 - Elsevier
Imaging can provide quantitative assessment of radiation-induced normal tissue effects.
Identifying an early sign of normal tissue damage with imaging would have the potential to …

Early prediction of tumor response to treatment: preclinical validation of 99mTc-duramycin

F Elvas, C Vangestel, K Pak, P Vermeulen… - Journal of Nuclear …, 2016 - Soc Nuclear Med
Noninvasive imaging of cell death can provide an early indication of the efficacy of tumor
treatment, aiding clinicians in distinguishing responding patients from nonresponding …

A novel murine model for localized radiation necrosis and its characterization using advanced magnetic resonance imaging

SC Jost, A Hope, E Kiehl, A Perry, S Travers… - International Journal of …, 2009 - Elsevier
PURPOSE: To develop a murine model of radiation necrosis using fractionated, subtotal
cranial irradiation; and to investigate the imaging signature of radiation-induced tissue …

[HTML][HTML] Re-assessment of chronic radio-induced tissue damage in a rat hindlimb model

B Phulpin, G Dolivet, PY Marie… - ExpErimEntal and …, 2010 - spandidos-publications.com
Radiotherapy is successfully used to treat neoplastic lesions, but may adversely affect
normal tissues within the irradiated volume. However, additional clinical and paraclinical …

Whole-body imaging of cell death provides a systemic, minimally invasive, dynamic, and near-real time indicator for chemotherapeutic drug toxicity

SE Johnson, A Ugolkov, CR Haney, G Bondarenko… - Clinical Cancer …, 2019 - AACR
Purpose: Response to toxicity in chemotherapies varies considerably from tissue to tissue
and from patient to patient. An ability to monitor the tissue damage done by chemotherapy …

[HTML][HTML] Wound trauma alters ionizing radiation dose assessment

JG Kiang, BR Garrison, TM Burns, M Zhai, IC Dews… - Cell & Bioscience, 2012 - Springer
Background Wounding following whole-body γ-irradiation (radiation combined injury, RCI)
increases mortality. Wounding-induced increases in radiation mortality are triggered by …