[PDF][PDF] Metabolic imaging with gallium-68-and indium-111-labeled low-density lipoprotein

SM Moerlein, A Daugherty, BE Sobel… - Journal of Nuclear …, 1991 - Soc Nuclear Med
MATERIALSAND METhODS Rabbfts New Zealand rabbits (Boswells Farms, Pacific, MO)
weigh ing 1.8 — 2.4 kg were used for biodistribution and scintigraphic experiments. Control …

[PDF][PDF] Indium-111-labeled LDL: a potential agent for imaging atherosclerotic disease and lipoprotein biodistribution

JM Rosen, SP Butler, GE Meinken… - Journal of Nuclear …, 1990 - Soc Nuclear Med
LDL was isQlatedfrom human hyperlipidemicplasma by sequential ultracentrifugation(14)
and dialyzed overnight against normal saline (pH 7.4) containing0. 1 mg/mbEDTA. Aliquots …

[PDF][PDF] Nuclear imaging analysis of human low-density lipoprotein biodistribution in rabbits and monkeys

RV Hay, RM Fleming, JW Ryan… - Journal of Nuclear …, 1991 - Soc Nuclear Med
MATERIALSAND METHODS Isolation and Derivatizatlon of Human LDL For these animal
studies, we electedto use human LDL rather than autologous rabbitor monkey LDL. Human …

Residualizing and non-residualizing analogues of low-density lipoprotein as iodine-123 radiopharmaceuticals for imaging LDL catabolism

SM Moerlein, KB Dalal, SN Ebbe, Y Yano… - International Journal of …, 1988 - Elsevier
Low-density lipoprotein (LDL) labeled via direct iodination or via the radioiodinated
residualizing moiety tyramine-cellobiose (TC) were compared in rabbits as potential 123 I …

[PDF][PDF] Effect of food intake on the tissue distribution of gallium-67: concise communication

RL Hayes, JJ Szymendera, BL Byrd - Journal of Nuclear Medicine, 1979 - Soc Nuclear Med
MATERIALSAND METHODS The animals used were CD2FI and C57BI/6 micet and male
Buffalo rats4 In each experiment the animals were matched as to age and sex to avoid any …

[PDF][PDF] Radiotracers for low density lipoprotein biodistribution studies in vivo: technetium-99m low density lipoprotein versus radioiodinated low density lipoprotein …

S Vallabhajosula, M Paidi, JJ Badimon… - Journal of nuclear …, 1988 - Soc Nuclear Med
In an attempt to characterize the in vivo behavior of [" Tc] low density lipoprotein (LDL),
biodistribution studies were performed in normal and hypercholesterolemic (HC) rabbits. In …

99mTc-low density lipoprotein: intracellularly trapped radiotracer for noninvasive imaging of low density lipoprotein metabolism in vivo

S Vallabhajosula, SJ Goldsmith - Seminars in nuclear medicine, 1990 - Elsevier
Low density lipoprotein (LDL) is the major transport protein for endogenous cholesterol in
human plasma. LDL can be radiolabeled with 99m Tc using sodium dithionite as a reducing …

[PDF][PDF] Differential uptake of gallium-67-labeled liposomes between tumors and inflammatory lesions in rats

I Ogihara, S Kojima, M Jay - Journal of nuclear medicine, 1986 - Soc Nuclear Med
Liposomes Between Tumors and InflammatoryLesions in Rats Page 1 he unique
characteristicsof liposornesas a micro capsule are being studied with keen interest and many …

Imaging of human atherosclerotic lesions using 123I-low-density lipoprotein

H Sinzinger, H Bergmann, J Kaliman… - European journal of …, 1986 - Springer
In patients suffering from clinically manifest atherosclerosis autologous LDL-labelling has
been done using 123 I. This technique allows localization of areas with an increased LDL …

Imaging of hepatic low density lipoprotein receptors by radionuclide scintiscanning in vivo.

M Huettinger, JR Corbett… - Proceedings of the …, 1984 - National Acad Sciences
The low density lipoprotein (LDL) receptor mediates the cellular uptake of plasma
lipoproteins that are derived from very low density lipoproteins (VLDL). Most of the functional …