Preclinical evaluation and first patient application of 99mTc-PSMA-I&S for SPECT imaging and radioguided surgery in prostate cancer
S Robu, M Schottelius, M Eiber, T Maurer… - Journal of Nuclear …, 2017 - Soc Nuclear Med
Initial studies in patients have demonstrated the suitability of 111In-PSMA-I&T (111In-
DOTAGA-(3-iodo-y)-fk-Sub (KuE))(PSMA is prostate-specific membrane antigen and I&T is …
DOTAGA-(3-iodo-y)-fk-Sub (KuE))(PSMA is prostate-specific membrane antigen and I&T is …
[HTML][HTML] [99cmTc]Tc-PSMA-I&S-SPECT/CT: experience in prostate cancer imaging in an outpatient center
P Werner, C Neumann, M Eiber, HJ Wester… - EJNMMI research, 2020 - Springer
Background Prostate-specific membrane antigen (PSMA) SPECT imaging in prostate cancer
(PCa) could be a valuable alternative in regions where access to PSMA-PET imaging is …
(PCa) could be a valuable alternative in regions where access to PSMA-PET imaging is …
[HTML][HTML] A Review on the Current State and Future Perspectives of [99mTc]Tc-Housed PSMA-i in Prostate Cancer
S Brunello, N Salvarese, D Carpanese, C Gobbi… - Molecules, 2022 - mdpi.com
Recently, prostate-specific membrane antigen (PSMA) has gained momentum in tumor
nuclear molecular imaging as an excellent target for both the diagnosis and therapy of …
nuclear molecular imaging as an excellent target for both the diagnosis and therapy of …
[HTML][HTML] [111In]PSMA-I&T: expanding the spectrum of PSMA-I&T applications towards SPECT and radioguided surgery
M Schottelius, M Wirtz, M Eiber, T Maurer, HJ Wester - EJNMMI research, 2015 - Springer
Background The relevance of prostate-specific membrane antigen (PSMA) targeting in the
clinical management of prostate cancer (PCa) is continually increasing, entailing the …
clinical management of prostate cancer (PCa) is continually increasing, entailing the …
Clinical translation of a PSMA inhibitor for 99mTc-based SPECT
G Ferro-Flores, M Luna-Gutiérrez… - Nuclear medicine and …, 2017 - Elsevier
Background Prostate-specific membrane antigen (PSMA) is highly over-expressed in
advanced prostate cancers. 68 Ga-labeled PSMA inhibitors (iPSMA) are currently used for …
advanced prostate cancers. 68 Ga-labeled PSMA inhibitors (iPSMA) are currently used for …
Synthesis and preclinical characterization of the PSMA-targeted hybrid tracer PSMA-I&F for nuclear and fluorescence imaging of prostate cancer
M Schottelius, A Wurzer, K Wissmiller… - Journal of Nuclear …, 2019 - Soc Nuclear Med
The prostate-specific membrane antigen (PSMA)–targeted radiotracers 68Ga/177Lu-PSMA-
I&T and 99mTc-PSMA-I&S (for i maging and s urgery) are currently successfully used for …
I&T and 99mTc-PSMA-I&S (for i maging and s urgery) are currently successfully used for …
[HTML][HTML] Radiation dosimetry and first therapy results with a 124I/131I-labeled small molecule (MIP-1095) targeting PSMA for prostate cancer therapy
CM Zechmann, A Afshar-Oromieh, T Armor… - European journal of …, 2014 - Springer
Introduction Since the prostate-specific membrane antigen (PSMA) is frequently over-
expressed in prostate cancer (PCa) several PSMA-targeting molecules are under …
expressed in prostate cancer (PCa) several PSMA-targeting molecules are under …
Radiolabeled enzyme inhibitors and binding agents targeting PSMA: effective theranostic tools for imaging and therapy of prostate cancer
MRA Pillai, R Nanabala, A Joy, A Sasikumar… - Nuclear medicine and …, 2016 - Elsevier
Because of the broad incidence, morbidity and mortality associated with prostate-derived
cancer, the development of more effective new technologies continues to be an important …
cancer, the development of more effective new technologies continues to be an important …
Effect of Chelators on the Pharmacokinetics of 99mTc-Labeled Imaging Agents for the Prostate-Specific Membrane Antigen (PSMA)
S Ray Banerjee, M Pullambhatla, CA Foss… - Journal of medicinal …, 2013 - ACS Publications
Technetium-99m, the most commonly used radionuclide in nuclear medicine, can be
attached to biologically important molecules through a variety of chelating agents, the choice …
attached to biologically important molecules through a variety of chelating agents, the choice …
[HTML][HTML] Joint EANM/SNMMI procedure guideline for the use of 177Lu-labeled PSMA-targeted radioligand-therapy (177Lu-PSMA-RLT)
C Kratochwil, WP Fendler, M Eiber, MS Hofman… - European journal of …, 2023 - Springer
Prostate-specific membrane antigen (PSMA) is expressed by the majority of clinically
significant prostate adenocarcinomas, and patients with target-positive disease can easily …
significant prostate adenocarcinomas, and patients with target-positive disease can easily …
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