Phenotyping of tumor biology in patients by multimodality multiparametric imaging: relationship of microcirculation, αvβ3 expression, and glucose metabolism

S Metz, C Ganter, S Lorenzen… - Journal of Nuclear …, 2010 - Soc Nuclear Med
Both dynamic contrast-enhanced (DCE) MRI and PET provide quantitative information on
tumor biology in living organisms. However, imaging biomarkers often neglect tissue …

[HTML][HTML] Multiparametric MR and PET imaging of intratumoral biological heterogeneity in patients with metastatic lung cancer using voxel-by-voxel analysis

S Metz, C Ganter, S Lorenzen, S van Marwick… - PLoS …, 2015 - journals.plos.org
Objectives Diffusion-weighted magnetic resonance imaging (DW-MRI) and imaging of
glucose metabolism by positron emission tomography (FDG-PET) provide quantitative …

Quantification of viable tumor microvascular characteristics by multispectral analysis

LR Berry, KH Barck, MA Go, J Ross… - … in Medicine: An …, 2008 - Wiley Online Library
Tumor heterogeneity complicates the quantification of tumor microvascular characteristics
assessed by dynamic contrast‐enhanced MRI (DCE‐MRI). To address this issue a novel …

[HTML][HTML] Multiparametric imaging of patient and tumour heterogeneity in non-small-cell lung cancer: quantification of tumour hypoxia, metabolism and perfusion

W van Elmpt, CML Zegers, B Reymen… - European journal of …, 2016 - Springer
Purpose Multiple imaging techniques are nowadays available for clinical in-vivo
visualization of tumour biology. FDG PET/CT identifies increased tumour metabolism …

[HTML][HTML] Fluorine-19 magnetic resonance imaging and positron emission tomography of tumor-associated macrophages and tumor metabolism

SH Shin, SH Park, SH Kang, SW Kim, M Kim… - Contrast Media & …, 2017 - hindawi.com
The presence of tumor-associated macrophages (TAMs) is significantly associated with poor
prognosis of tumors. Currently, magnetic resonance imaging-(MRI-) based TAM imaging …

A population-based Gaussian mixture model incorporating 18F-FDG PET and diffusion-weighted MRI quantifies tumor tissue classes

MR Divine, P Katiyar, U Kohlhofer… - Journal of Nuclear …, 2016 - Soc Nuclear Med
The aim of our study was to create a novel Gaussian mixture modeling (GMM) pipeline to
model the complementary information derived from18F-FDG PET and diffusion-weighted …

[HTML][HTML] Decoding the interdependence of multiparametric magnetic resonance imaging to reveal patient subgroups correlated with survivals

C Li, S Wang, P Liu, T Torheim, NR Boonzaier… - Neoplasia, 2019 - Elsevier
Glioblastoma is highly heterogeneous in microstructure and vasculature, creating various
tumor microenvironments among patients, which may lead to different phenotypes. The …

Simultaneous mapping of vasculature, hypoxia, and proliferation using dynamic susceptibility contrast MRI, 18F-FMISO PET, and 18F-FLT PET in relation to contrast …

S Collet, JS Guillamo, DH Berro… - Journal of Nuclear …, 2021 - Soc Nuclear Med
Conventional MRI plays a key role in the management of patients with high-grade glioma,
but multiparametric MRI and PET tracers could provide further information to better …

Quantification of tumor tissue populations by multispectral analysis

RAD Carano, AL Ross, J Ross… - … in Medicine: An …, 2004 - Wiley Online Library
Tumor heterogeneity complicates the quantification of a therapeutic response by MRI. To
address this issue, a novel approach has been developed that combines MR diffusion …

[HTML][HTML] Multimodal functional imaging for cancer/tumor microenvironments based on MRI, EPRI, and PET

K Matsumoto, JB Mitchell, MC Krishna - Molecules, 2021 - mdpi.com
Radiation therapy is one of the main modalities to treat cancer/tumor. The response to
radiation therapy, however, can be influenced by physiological and/or pathological …