Treatment-related uptake of O-(2-18F-fluoroethyl)-l-tyrosine and l-[methyl-3H]-methionine after tumor resection in rat glioma models

S Geisler, C Stegmayr, N Niemitz… - Journal of nuclear …, 2019 - Soc Nuclear Med
Assessment of residual tumor after resection of cerebral gliomas can be difficult with MRI
and may be improved by amino acid PET. The aim of this experimental study was to …

Flare phenomenon in O-(2-18F-fluoroethyl)-l-tyrosine PET after resection of gliomas

CP Filss, AK Schmitz, G Stoffels… - Journal of nuclear …, 2020 - Soc Nuclear Med
PET using O-(2-18F-fluoroethyl)-l-tyrosine (18F-FET) is useful to detect residual tumor tissue
after glioma resection. Recent animal experiments detected reactive changes in 18F-FET …

Comparison of fluorotyrosines and methionine uptake in F98 rat gliomas

KJ Langen, M Jarosch, H Mühlensiepen… - Nuclear medicine and …, 2003 - Elsevier
The transport mechanisms of O-(2-[18F] fluoroethyl)-L-tyrosine (FET) and 2-[18F] fluoro-L-
tyrosine (FTyr) were compared to those of [3H]-Methyl-L-methionine (MET) in F98 rat glioma …

Uptake of O-(2-[18F] fluoroethyl)-L-tyrosine in reactive astrocytosis in the vicinity of cerebral gliomas

MD Piroth, J Prasath, A Willuweit, G Stoffels… - Nuclear medicine and …, 2013 - Elsevier
Abstract PET using O-(2-[18 F] fluoroethyl)-L-tyrosine (18 F-FET) allows improved imaging of
tumor extent of cerebral gliomas in comparison to MRI. In experimental brain infarction and …

O-(2-[18F]Fluoroethyl)-l-tyrosine and l-[methyl-11C]methionine uptake in brain tumours: initial results of a comparative study

WA Weber, HJ Wester, AL Grosu, M Herz… - European journal of …, 2000 - Springer
O-(2-[18 F] Fluoroethyl)-l-tyrosine (FET) is a recently described amino acid analogue that
has shown high accumulation in animal tumours. The aim of this study was to compare the …

Uptake and tracer kinetics of O-(2-18F-fluoroethyl)-l-tyrosine in meningiomas: preliminary results

JF Cornelius, G Stoffels, C Filß, N Galldiks… - European journal of …, 2015 - Springer
Abstract Purpose O-(2-[18 F] Fluoroethyl)-l-tyrosine (18 F-FET) is a well-established PET
tracer for the imaging of cerebral gliomas, but little is known about 18 F-FET uptake in …

Reproducibility of O-(2-18F-fluoroethyl)-L-tyrosine uptake kinetics in brain tumors and influence of corticoid therapy: an experimental study in rat gliomas

C Stegmayr, M Schöneck, D Oliveira… - European journal of …, 2016 - Springer
Purpose Positron emission tomography (PET) using O-(2-18 F-fluoroethyl)-L-tyrosine (18 F-
FET) is a well-established method for the diagnostics of brain tumors. This study investigates …

Influence of blood-brain barrier permeability on O-(2-18F-fluoroethyl)-L-tyrosine uptake in rat gliomas

C Stegmayr, U Bandelow, D Oliveira… - European journal of …, 2017 - Springer
Abstract Purpose O-(2-18 F-fluoroethyl)-L-tyrosine (18 F-FET) is an established tracer for the
diagnosis of brain tumors with PET. This study investigates the influence of blood-brain …

An interindividual comparison of O-(2-[18F] Fluoroethyl)-L-Tyrosine (FET)–and L-[Methyl-11C] methionine (MET)–PET in patients with brain gliomas and metastases

AL Grosu, ST Astner, E Riedel, C Nieder… - International Journal of …, 2011 - Elsevier
PURPOSE: L-[methyl-11C] methionine (MET)–positron emission tomography (PET) has a
high sensitivity and specificity for imaging of gliomas and metastatic brain tumors. The short …

Analysis of 18F-FET PET for grading of recurrent gliomas: is evaluation of uptake kinetics superior to standard methods?

G Pöpperl, FW Kreth, J Herms, W Koch… - Journal of nuclear …, 2006 - Soc Nuclear Med
The aim of the present study was to evaluate whether extended analyses of O-(2-18F-
fluoroethyl)-l-tyrosine (FET) uptake kinetics provide results superior to those of standard …