Clinical relevance of targeting the gastrin-releasing peptide receptor, somatostatin receptor 2, or chemokine CXC motif receptor 4 in breast cancer for imaging and …

SU Dalm, AM Sieuwerts, MP Look… - Journal of Nuclear …, 2015 - Soc Nuclear Med
Imaging and therapy using radioligands targeting receptors overexpressed on tumor cells is
successfully applied in neuroendocrine tumor patients. Because expression of the gastrin …

[HTML][HTML] Prospects of targeting the gastrin releasing peptide receptor and somatostatin receptor 2 for nuclear imaging and therapy in metastatic breast cancer

SU Dalm, WAME Schrijver, AM Sieuwerts, MP Look… - PloS one, 2017 - journals.plos.org
Background The gastrin releasing peptide receptor (GRPR) and the somatostatin receptor 2
(SSTR2) are overexpressed on primary breast cancer (BC), making them ideal candidates …

In vitro and in vivo application of radiolabeled gastrin-releasing peptide receptor ligands in breast cancer

SU Dalm, JWM Martens, AM Sieuwerts… - Journal of Nuclear …, 2015 - Soc Nuclear Med
Breast cancer (BC) consists of multiple subtypes defined by various molecular
characteristics, for instance, estrogen receptor (ER) expression. Methods for visualizing BC …

Expression of gastrin-releasing peptide receptor in breast cancer and its association with pathologic, biologic, and clinical parameters: a study of 1,432 primary tumors

C Morgat, G MacGrogan, V Brouste… - Journal of Nuclear …, 2017 - Soc Nuclear Med
A growing body of evidence suggests that gastrin-releasing peptide receptor (GRPR) might
be a valuable target in breast cancer. To understand which patients can be potential …

[HTML][HTML] Gastrin-releasing peptide receptor as a theranostic target in breast cancer: a systematic scoping review

C Baun, M Naghavid-Behzad, MG Hildebrandt… - Seminars in Nuclear …, 2024 - Elsevier
The gastrin-releasing peptide receptor (GRPR) is known to be overexpressed in breast
cancer, making it a promising target for both imaging and therapy within a theranostic …

Gastrin-releasing peptide receptor imaging in human breast carcinoma versus immunohistochemistry

C Van de Wiele, P Phonteyne, P Pauwels… - Journal of Nuclear …, 2008 - Soc Nuclear Med
This study reports on the uptake of 99mTc-RP527 by human breast carcinoma and its
relationship to gastrin-releasing peptide receptor (GRP-R) expression as measured by …

SSTR-mediated imaging in breast cancer: is there a role for radiolabeled somatostatin receptor antagonists?

SU Dalm, J Haeck, GN Doeswijk… - Journal of Nuclear …, 2017 - Soc Nuclear Med
Recent studies have shown enhanced tumor targeting by novel somatostatin receptor
(SSTR) antagonists compared with clinically widely used agonists. However, these results …

[HTML][HTML] Gastrin-releasing peptide receptor imaging in breast cancer using the receptor antagonist 68Ga-RM2 and PET

C Stoykow, T Erbes, HR Maecke, S Bulla… - Theranostics, 2016 - ncbi.nlm.nih.gov
Introduction: The gastrin-releasing peptide receptor (GRPR) is overexpressed in breast
cancer. The present study evaluates GRPR imaging as a novel imaging modality in breast …

Gastrin-releasing peptide receptor agonists and antagonists for molecular imaging of breast and prostate cancer: from pre-clinical studies to translational perspectives

J Gorica, MS De Feo, L Filippi… - Expert Review of …, 2022 - Taylor & Francis
Introduction Prostate and breast cancer represent a leading cause of cancer-related death
worldwide with a dramatic social and demographic impact. Gastrin-releasing peptide …

[HTML][HTML] Phase I Trial of [99mTc]Tc-maSSS-PEG2-RM26, a Bombesin Analogue Antagonistic to Gastrin-Releasing Peptide Receptors (GRPRs), for SPECT Imaging …

V Chernov, A Rybina, R Zelchan, A Medvedeva… - Cancers, 2023 - mdpi.com
Simple Summary Prostate and breast cancers are the most common malignancies. Accurate
diagnosis and staging of diseases are important for the prognosis and determination of …