Partition model–based 99mTc-MAA SPECT/CT predictive dosimetry compared with 90Y TOF PET/CT posttreatment dosimetry in radioembolization of hepatocellular …

S Gnesin, L Canetti, S Adib, N Cherbuin… - Journal of Nuclear …, 2016 - Soc Nuclear Med
90Y-microsphere selective internal radiation therapy (SIRT) is a valuable treatment in
unresectable hepatocellular carcinoma (HCC). Partition-model predictive dosimetry relies …

Prediction of tumor response and patient outcome after radioembolization of hepatocellular carcinoma using 90Y-PET-computed tomography dosimetry

P d'Abadie, S Walrand, M Hesse, L Annet… - Nuclear medicine …, 2021 - journals.lww.com
Aim 90Y-radioembolization using glass or resin microspheres is increasingly used for the
treatment of hepatocellular carcinoma (HCC). The aim of this retrospective study is to …

[HTML][HTML] Impact of the dosimetry approach on the resulting 90Y radioembolization planned absorbed doses based on 99mTc-MAA SPECT-CT: is there agreement …

V Morán, E Prieto, L Sancho, M Rodríguez-Fraile… - EJNMMI physics, 2020 - Springer
Background Prior radioembolization, a simulation using 99m Tc-macroaggregated albumin
as 90 Y-microspheres surrogate is performed. Gamma scintigraphy images (planar, SPECT …

Image-guided personalized predictive dosimetry by artery-specific SPECT/CT partition modeling for safe and effective 90Y radioembolization

YH Kao, AEH Tan, MC Burgmans, FG Irani… - Journal of Nuclear …, 2012 - Soc Nuclear Med
Compliance with radiobiologic principles of radionuclide internal dosimetry is fundamental
to the success of 90Y radioembolization. The artery-specific SPECT/CT partition model is an …

[HTML][HTML] Analysis of differences between 99mTc-MAA SPECT- and 90Y-microsphere PET-based dosimetry for hepatocellular carcinoma selective internal radiation …

M Kafrouni, C Allimant, M Fourcade, S Vauclin, B Guiu… - EJNMMI research, 2019 - Springer
Background The aim of this study was to compare predictive and post-treatment dosimetry
and analyze the differences, investigating factors related to activity preparation and delivery …

[HTML][HTML] 3D image-based dosimetry for Yttrium-90 radioembolization of hepatocellular carcinoma: Impact of imaging method on absorbed dose estimates

J Brosch, A Gosewisch, L Kaiser, M Seidensticker… - Physica Medica, 2020 - Elsevier
Background To improve therapy outcome of Yttrium-90 selective internal radiation therapy
(90 Y SIRT), patient-specific post-therapeutic dosimetry is required. For this purpose, various …

Predictive value of 99mTc-MAA SPECT for 90Y-labeled resin microsphere distribution in radioembolization of primary and secondary hepatic tumors

H Ilhan, A Goritschan, P Paprottka… - Journal of Nuclear …, 2015 - Soc Nuclear Med
This study analyzed the predictive value of 99mTc-labeled macroaggregated albumin
(99mTc-MAA) SPECT for 90Y-labeled resin microsphere therapy (radioembolization) by …

[HTML][HTML] Predictive value of 99mTc-MAA-based dosimetry in personalized 90Y-SIRT planning for liver malignancies

M Riveira-Martin, A Akhavanallaf, Z Mansouri… - EJNMMI research, 2023 - Springer
Background Selective internal radiation therapy with 90Y radioembolization aims to
selectively irradiate liver tumours by administering radioactive microspheres under the …

Planning dosimetry for 90Y radioembolization with glass microspheres: Evaluating the fidelity of 99mTc‐MAA and partition model predictions

MA Thomas, A Mahvash, M Abdelsalam… - Medical …, 2020 - Wiley Online Library
Purpose 99mTc‐MAA‐SPECT/CT may be used in 90Y‐glass microsphere
radioembolization treatment planning to assess perfused liver volumes and absorbed dose …

Prognostic utility of 90Y radioembolization dosimetry based on fusion 99mTc-macroaggregated albumin–99mTc-sulfur colloid SPECT

MGEH Lam, ML Goris, AH Iagaru… - Journal of Nuclear …, 2013 - Soc Nuclear Med
Planning hepatic 90Y radioembolization activity requires balancing toxicity with efficacy. We
developed a dual-tracer SPECT fusion imaging protocol that merges data on radioactivity …