Comparison of uptake of multiple clinical radiotracers into brown adipose tissue under cold-stimulated and nonstimulated conditions

S Baba, JM Engles, DL Huso, T Ishimori… - Journal of Nuclear …, 2007 - Soc Nuclear Med
Our objective was to determine whether multiple clinically useful radiotracers accumulate in
brown adipose tissue (BAT) and to assess their uptake in rats kept at room temperature or …

Combining 123I-metaiodobenzylguanidine SPECT/CT and 18F-FDG PET/CT for the assessment of brown adipose tissue activity in humans during cold exposure

WM Admiraal, F Holleman, L Bahler… - Journal of Nuclear …, 2013 - Soc Nuclear Med
Brown adipose tissue (BAT) has become a focus of research in the hope of finding a new
target to fight obesity. Metabolic BAT activity can be visualized with 18F-FDG PET/CT …

Temporal relation between temperature change and FDG uptake in brown adipose tissue

SH Kim, BR Krynyckyi, J Machac, CK Kim - European journal of nuclear …, 2008 - Springer
Objectives It has been reported that the prevalence of 18 F fluorodeoxyglucose (FDG)
uptake in brown adipose tissue (BAT) is related to outdoor temperature, ie, more frequent …

CT Hounsfield units of brown adipose tissue increase with activation: preclinical and clinical studies

S Baba, HA Jacene, JM Engles, H Honda… - Journal of Nuclear …, 2010 - Soc Nuclear Med
Brown adipose tissue (BAT) densities assessed as CT Hounsfield units (HUs) were
evaluated in a rodent model and in patients to determine whether HUs changed in relation …

Fasting and postprandial activity of brown adipose tissue in healthy men

A Vrieze, JE Schopman, WM Admiraal… - Journal of Nuclear …, 2012 - Soc Nuclear Med
The role of brown adipose tissue (BAT) in adult metabolism is poorly understood. This study
aimed to examine the differential effects of an overnight fast and the postprandial state on …

Thermal imaging is a noninvasive alternative to PET/CT for measurement of brown adipose tissue activity in humans

J Law, DE Morris, C Izzi-Engbeaya… - Journal of Nuclear …, 2018 - Soc Nuclear Med
Obesity and its metabolic consequences are a major cause of morbidity and mortality. Brown
adipose tissue (BAT) utilizes glucose and free fatty acids to produce heat, thereby increasing …

Brown adipose tissue and nuclear medicine imaging

WA Weber - Journal of Nuclear Medicine, 2004 - Soc Nuclear Med
During the last 2 years, brown adipose tissue (BAT) has received considerable attention in
the field of nuclear medicine. BAT has been shown to accumulate 18F-FDG (1–4) …

Measurement of brown adipose tissue activity using microwave radiometry and 18F-FDG PET/CT

JP Crandall, P Gajwani, JP Leal… - Journal of Nuclear …, 2018 - Soc Nuclear Med
The aim of this study was to evaluate the operating characteristics of a microwave
radiometry system in the noninvasive assessment of activated and nonactivated brown …

15O PET measurement of blood flow and oxygen consumption in cold-activated human brown fat

O Muzik, TJ Mangner, WR Leonard… - Journal of Nuclear …, 2013 - Soc Nuclear Med
Although it has been believed that brown adipose tissue (BAT) depots disappear shortly
after the perinatal period in humans, PET imaging using the glucose analog 18F-FDG has …

Quantification of human and rodent brown adipose tissue function using 99mTc-methoxyisobutylisonitrile SPECT/CT and 18F-FDG PET/CT

AM Cypess, AN Doyle, CA Sass… - Journal of Nuclear …, 2013 - Soc Nuclear Med
For brown adipose tissue (BAT) to be effective at consuming calories, its blood flow must
increase enough to provide sufficient fuel to sustain energy expenditure and also transfer …