99mTc-labeled small-molecule inhibitors of prostate-specific membrane antigen: pharmacokinetics and biodistribution studies in healthy subjects and patients with …
S Vallabhajosula, A Nikolopoulou… - Journal of Nuclear …, 2014 - Soc Nuclear Med
Prostate-specific membrane antigen (PSMA) is a well-established target for developing
radiopharmaceuticals for imaging and therapy of prostate cancer (PCa). We have recently …
radiopharmaceuticals for imaging and therapy of prostate cancer (PCa). We have recently …
99mTc-labeled small-molecule inhibitors of prostate-specific membrane antigen for molecular imaging of prostate cancer
SM Hillier, KP Maresca, G Lu, RD Merkin… - Journal of Nuclear …, 2013 - Soc Nuclear Med
Prostate-specific membrane antigen (PSMA) is highly expressed in prostate cancer, and
small-molecule radiopharmaceuticals targeting PSMA rapidly detect the location and extent …
small-molecule radiopharmaceuticals targeting PSMA rapidly detect the location and extent …
99mTc-labeled PSMA inhibitor: Biokinetics and radiation dosimetry in healthy subjects and imaging of prostate cancer tumors in patients
C Santos-Cuevas, J Davanzo, G Ferro-Flores… - Nuclear Medicine and …, 2017 - Elsevier
The prostate-specific membrane antigen (PSMA) is expressed in epithelial cells of the
prostate and highly overexpressed in 95% of advanced prostate cancers. The aims of this …
prostate and highly overexpressed in 95% of advanced prostate cancers. The aims of this …
Radiolabeled Small-Molecule Ligands for Prostate-Specific Membrane Antigen: In vivo Imaging in Experimental Models of Prostate Cancer
Purpose: Prostate-specific membrane antigen (PSMA) is a cell surface protein that is
overexpressed in prostate cancer, including hormone-refractory and metastatic disease. Our …
overexpressed in prostate cancer, including hormone-refractory and metastatic disease. Our …
99mTc-labeling and evaluation of a HYNIC modified small-molecular inhibitor of prostate-specific membrane antigen
X Xu, J Zhang, S Hu, S He, X Bao, G Ma, J Luo… - Nuclear medicine and …, 2017 - Elsevier
Introduction Prostate-specific membrane antigen (PSMA) is a well-established target in the
development of radiopharmaceuticals for the diagnosis and therapy of prostate cancer …
development of radiopharmaceuticals for the diagnosis and therapy of prostate cancer …
Synthesis and evaluation of technetium-99m-and rhenium-labeled inhibitors of the prostate-specific membrane antigen (PSMA)
SR Banerjee, CA Foss, M Castanares… - Journal of medicinal …, 2008 - ACS Publications
The prostate-specific membrane antigen (PSMA) is increasingly recognized as a viable
target for imaging and therapy of cancer. We prepared seven 99mTc/Re-labeled compounds …
target for imaging and therapy of cancer. We prepared seven 99mTc/Re-labeled compounds …
Clinical translation of a PSMA inhibitor for 99mTc-based SPECT
G Ferro-Flores, M Luna-Gutiérrez… - Nuclear medicine and …, 2017 - Elsevier
Background Prostate-specific membrane antigen (PSMA) is highly over-expressed in
advanced prostate cancers. 68 Ga-labeled PSMA inhibitors (iPSMA) are currently used for …
advanced prostate cancers. 68 Ga-labeled PSMA inhibitors (iPSMA) are currently used for …
Effect of Chelators on the Pharmacokinetics of 99mTc-Labeled Imaging Agents for the Prostate-Specific Membrane Antigen (PSMA)
S Ray Banerjee, M Pullambhatla, CA Foss… - Journal of medicinal …, 2013 - ACS Publications
Technetium-99m, the most commonly used radionuclide in nuclear medicine, can be
attached to biologically important molecules through a variety of chelating agents, the choice …
attached to biologically important molecules through a variety of chelating agents, the choice …
Recent developments of prostate-specific membrane antigen (PSMA)-specific radiopharmaceuticals for precise imaging and therapy of prostate cancer: an overview
SM Okarvi - Clinical and Translational Imaging, 2019 - Springer
Despite significant research activities and subsequent progress made in the fight against
cancer over the last few decades, prostate cancer remains a major health-related problem …
cancer over the last few decades, prostate cancer remains a major health-related problem …
Glu-ureido–based inhibitors of prostate-specific membrane antigen: lessons learned during the development of a novel class of low-molecular-weight theranostic …
K Kopka, M Benešová, C Bařinka… - Journal of Nuclear …, 2017 - Soc Nuclear Med
In recent years, several radioligands targeting prostate-specific membrane antigen (PSMA)
have been clinically introduced as a new class of theranostic radiopharmaceuticals for the …
have been clinically introduced as a new class of theranostic radiopharmaceuticals for the …
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