Molecular targeting with radionuclides: state of the science

SH Britz-Cunningham, SJ Adelstein - Journal of Nuclear Medicine, 2003 - Soc Nuclear Med
Inherent in the application of advances in biomedical science to nuclear medicine is the
concept of molecular targeting: the in vivo concentration of labeled tracer by a gene, its …

The role of nuclear medicine in modern therapy of cancer

G Kramer-Marek, J Capala - Tumor Biology, 2012 - Springer
Nuclear medicine is a multidisciplinary field that develops and uses instrumentation and
tracers (radiopharmaceuticals) to study physiological processes and noninvasively …

Towards the goal of cancer-specific imaging and therapy

KE Britton - Nuclear medicine communications, 1997 - journals.lww.com
Imaging and therapy of cancer using radionuclide-labelled compounds is surveyed. The
current state of knowledge concerning the cancerous process, the subtle differences …

A pragmatic perspective on molecular targeted radionuclide therapy

SM Larson, EP Krenning - Journal of Nuclear Medicine, 2005 - Soc Nuclear Med
This collection of reviews and papers on targeted radionuclide therapy provides a snapshot
of the current status of modern clinical applications of therapeutic nuclear medicine. The …

Radiopharmaceuticals for molecular imaging

YS Lee - The Open Nuclear Medicine Journal, 2010 - benthamopen.com
Radiopharmaceuticals for molecular imaging involve careful consideration of the following
two factors: radionuclide selection and specificity to the molecular target. In selecting a …

[HTML][HTML] Clinical advances and perspectives in targeted radionuclide therapy

N Lepareur, B Ramée, M Mougin-Degraef… - Pharmaceutics, 2023 - mdpi.com
Targeted radionuclide therapy has become increasingly prominent as a nuclear medicine
subspecialty. For many decades, treatment with radionuclides has been mainly restricted to …

Targeted radionuclide therapy

LE Williams, GL DeNardo, RF Meredith - Medical physics, 2008 - Wiley Online Library
Targeted radionuclide therapy (TRT) seeks molecular and functional targets within patient
tumor sites. A number of agents have been constructed and labeled with beta, alpha, and …

[HTML][HTML] Radiolabeling strategies for tumor-targeting proteinaceous drugs

G Sugiura, H Kühn, M Sauter, U Haberkorn, W Mier - Molecules, 2014 - mdpi.com
Owing to their large size proteinaceous drugs offer higher operative information content
compared to the small molecules that correspond to the traditional understanding of …

Advances in anticancer radiopharmaceuticals

MR Jackson, N Falzone, KA Vallis - Clinical Oncology, 2013 - Elsevier
This review highlights recent progress in the development of anticancer
radiopharmaceuticals. Molecularly targeted radiotherapy refers to the selective delivery of …

Receptor radionuclide therapy of tumors: a road from basic research to clinical applications

L Bodei, G Paganelli, G Mariani - Journal of Nuclear Medicine, 2006 - Soc Nuclear Med
Journal of Nuclear Medicine of the article by Cescato et al.(1) prompts some considerations
on receptorguided tumor targeting with radionuclides. The term receptor-guided tumor …