Reduced blood flow and preserved vasoreactivity characterize oxygen hypometabolism due to incomplete infarction in occlusive carotid artery diseases

S Kuroda, T Shiga, T Ishikawa, K Houkin… - Journal of Nuclear …, 2004 - Soc Nuclear Med
Recent studies have clarified that hemodynamically compromised patients are at high risk
for subsequent stroke. The acetazolamide test is widely used to detect the patients with …

Cerebral oxygen metabolism and neuronal integrity in patients with impaired vasoreactivity attributable to occlusive carotid artery disease

S Kuroda, T Shiga, K Houkin, T Ishikawa, C Katoh… - Stroke, 2006 - Am Heart Assoc
Background and Purpose—It is still unclear that impaired cerebrovascular reactivity (CVR) to
acetazolamide is comparable to elevated oxygen extraction fraction (OEF) on positron …

Combination of a mean transit time measurement with an acetazolamide test increases predictive power to identify elevated oxygen extraction fraction in occlusive …

M Hokari, S Kuroda, T Shiga, N Nakayama… - Journal of Nuclear …, 2008 - Soc Nuclear Med
Reduced cerebral blood flow and cerebrovascular reactivity to acetazolamide have been
used as predictors for subsequent ischemic stroke in patients with occlusive carotid artery …

Clinical significance of cerebrovascular reserve in acetazolamide challenge —comparison with acetazolamide challenge H2O-PET and Gas-PET—

M Imaizumi, K Kitagawa, N Oku, K Hashikawa… - Annals of nuclear …, 2004 - Springer
Objective The response of cerebral blood flow (CBF) to acetazolamide (ACZ) challenge is
frequently determined in clinical settings to evaluate cerebrovascular reserve (CVR). A …

Acetazolamide Reactivity on 123I-IMP Single Photon Emission Computed Tomography in Patients with Major Cerebral Artery Occlusive Disease: Correlation with …

T Hirano, K Minematsu, Y Hasegawa… - Journal of Cerebral …, 1994 - journals.sagepub.com
Single photon emission computed tomography (SPECT) with acetazolamide challenge has
increasingly been used for evaluating hemodynamic reserve in stroke patients. The …

Impact of oxygen extraction fraction on long-term prognosis in patients with reduced blood flow and vasoreactivity because of occlusive carotid artery disease

M Hokari, S Kuroda, T Shiga, N Nakayama, N Tamaki… - Surgical neurology, 2009 - Elsevier
BACKGROUND: Reduced cerebral blood flow and cerebrovascular reactivity to
acetazolamide (type 3 ischemia) is believed as an independent predictor for subsequent …

PET OEF reactivity for hemodynamic compromise in occlusive vascular disease

EM Nemoto, H Yonas, RR Pindzola… - Journal of …, 2007 - Wiley Online Library
ABSTRACT Background and Purpose. Hemodynamic compromise in symptomatic patients
with occlusive vascular disease (OVD) identified by cerebrovascular reserve (CVR) and …

Detection of Misery Perfusion With Split-Dose 123I-Iodoamphetamine Single-Photon Emission Computed Tomography in Patients With Carotid Occlusive Diseases

M Imaizumi, K Kitagawa, K Hashikawa, N Oku… - Stroke, 2002 - Am Heart Assoc
Background and Purpose—Patients with carotid occlusive disease and stage 2 cerebral
hemodynamic failure, characterized by an increased oxygen extraction fraction (OEF) as …

Identification of hemodynamic compromise by cerebrovascular reserve and oxygen extraction fraction in occlusive vascular disease

EM Nemoto, H Yonas, H Kuwabara… - Journal of Cerebral …, 2004 - journals.sagepub.com
Cerebrovascular reserve (CVR) and oxygen extraction fraction (OEF) are used to identify
hemodynamic compromise in symptomatic patients with carotid occlusive vascular disease …

The effect of acetazolamide on regional cerebral blood oxygenation at rest and under stimulation as assessed by MRI

H Bruhn, A Kleinschmidt, H Boecker… - Journal of Cerebral …, 1994 - journals.sagepub.com
The sensitivity of gradient echo magnetic resonance imaging (MRI) to changes in cerebral
blood oxygenation (CBO) has been introduced for mapping functional brain activation. Here …